EurekaMag.com logo
+ Site Statistics
References:
47,893,527
Abstracts:
28,296,643
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Spectral study of poly cyclic hydro carbon lipid interaction in tumor bearing animals






Vestnik Moskovskogo Universiteta Seriya VI Biologiya Pochvovedenie 30(5): 105-106

Spectral study of poly cyclic hydro carbon lipid interaction in tumor bearing animals

Incubation at 37.degree. C of 20-methylcholanthrene with blood or liver lipids of rats with Pliss lymphosarcoma leads to disappearance of the carcinogen.


Accession: 006459958



Related references

Imai, Y.; Iizuka, T.; Ishimura, Y., 1982: Interaction of poly cyclic hydro carbons with cytochrome p 450 2. flash photolysis studies on various hydro carbon bound cytochrome p 448 1 carbon mon oxide compounds. Effects of aromatic hydrocarbon binding on the photodissociability of CO from ferrous carbonmonoxy cytochrome P-4481 from rabbits and their subsequent recombination reactions were studied with the aid of the flash photolysis technique. Size and st...

Imai, Y., 1982: Interaction of poly cyclic hydro carbons with cytochrome p 450 3. effects of hydro carbon binding on the interaction of some ligands with cytochrome p 4481 heme. The binding of polycyclic hydrocarbons to cytochrome P-4481 from rabbits affected the interaction of exogenous ligands, such as ethyl isocyanide and CO in the ferrous state and 1-methyl imidazole in the ferric state, with the heme to various exten...

Bresnick, E.; Vaught, J.B.; Chuang, A.H.L.; Stoming, T.A.; Bockman, D.; Mukhtar, H., 1977: Nuclear aryl hydro carbon hydroxylase and interaction of poly cyclic hydro carbons with nuclear components. Aryl hydrocarbon hydroxylase (AHH) activity was demonstrated in the nucleus by a specific histofluorescent technique. The nuclear AHH is present at 15-20% of the activity of the microsomal enzyme. The properties of the nuclear and microsomal AHH w...

Wiebel F.J.; Gelboin H.V., 1974: Enzyme induction and poly cyclic hydro carbon metabolism in cell culture experimental animals and man. Montesano, R And L Tomatis (Ed ) Iarc (International Agency For Research on Cancer) Scientific Publications, No 10 Chemical Carcinogenesis Essays Proceedings Of A Workshop on Approaches to Assess The Significance Of Experimental Chemical Carcinogenesis Data For Man Brussels, Belgium, Dec 10-12, 1973 Xiv+230p Illus International Agency For Research on Cancer: Lyon, France (Dist By World Health Organization: Geneva, Switzerland ) 57-82

Thorgeirsson S.S.; Atlas S.A.; Boobis A.R.; Felton J.S.; Nebert D.W., 1975: Varying substrate specificities of cytochrome p 1 450 in poly cyclic hydro carbon treated animals of 5 species. Pharmacologist 17(2): 217

Novikov, V.E.; Semin, B.K.; Tarusov, B.N.; Esakova, T.D.; Petrusevich-Yu, M., 1975: Interaction of poly cyclic hydro carbons and liver lipids in animals during early stages of carcinogenesis. In rats injected with 20-methylcholanthrene (50 mg/kg) 2 carcinogenic phases were observed in blood and liver lipids, each corresponding to an increase in hydroxylacting activity of the microsomal fraction. Increase in carcinogen level in liver wa...

Slaga T.J.; Berry D.L.; Juchau M.R.; Thompson S., 1975: Poly cyclic hydro carbon metabolism and tumor initiation in mouse skin. Pharmacologist 17(2): 184

Kano, I.; Gielen, J.E.; Yagi, H.; Jerina, D.M.; Nebert, D.W., 1977: Sub cellular events occurring during aryl hydro carbon hydroxylase ec 1.14.14.2 induction no requirement for metabolism of poly cyclic hydro carbon inducer. The induction of aryl hydrocarbon (benzo[a]pyrene) hydroxylase (EC 1.14.14.2) activity in the rat Reuber hepatoma H-4-II-E established cell line was studied with 3-methylcholanthrene and its K-region oxide and diol and with benzo[a]pyrene and 23 o...

Pero, R.W.; Bryngelsson, T.; Rudduck, C.; Levan, G., 1978: Poly cyclic hydro carbon induced rat sarcomas correlated to disturbances in the deoxy adenylate regions of the tumor dna. Ten groups containing a total of 51 rat sarcomas induced by polycyclic hydrocarbons were examined for inducing agent-related abnormalities in their DNA. The levels of deoxyadenylate (dA) regions in normal and tumor rat DNA were estimated from anne...

Milo, G.E.; Blakeslee, J.; Yohn, D.S.; Dipaolo, J.A., 1978: Biochemical activation of aryl hydro carbon hydroxylase activity cellular distribution of poly nuclear hydro carbon metabolites and dna damage by poly nuclear hydro carbon products in human cells in vitro. Carcinogenic polynuclear hydrocarbons [7,12-dimethylbenzanthracene, 3-methylcholanthrene and benzo(a)pyrene] were added to human skin fibroblast cell cultures. Only benzo(a)pyrene at 10 .mu.g/ml or above induced mixed function hydroxylase activity...