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Spectrin from sea urchin eggs

, : Spectrin from sea urchin eggs. Biomedical Research (Tokyo) 7(1): 65-68

A protein which resembles spectrin from mammalian erythrocyte or brain was found in sea urchin eggs. This protein comigrated with mammalian .alpha.-spectrin on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, bound brain calmodulin in the presence of both 6 M urea and Ca2+, and cross-reacted with antibodies against chicken erythrocyte spectrin. It appeared to be a flexible, rod-like molecule as observed by low-angle rotary shadowing electron microscopy. Attachment of this protein to the actin filament was also observed.

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