EurekaMag.com logo
+ Translate

Spectro fluorometric determination of thio purines part 1 6 thio guanine


, : Spectro fluorometric determination of thio purines part 1 6 thio guanine. Talanta 23(5): 383-386

6-Thioguanine is oxidized to the corresponding S-oxide by reaction with H2O2 in 50% acetic acid at 50.degree. C for 5 min. The S-oxide is highly fluorescent and a rapid and sensitive fluorometric method of determination of thioguanine at the ng per ml level in water and .mu.g per ml level in serum and urine was developed on the basis of this reaction. The method was used for the determination of thioguanine in blood and urine samples in leukemia patients.

(PDF 0-2 workdays service)

Accession: 006460077

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Sekine T.; Arai Y.; Saneyoshi M., 1973: Effect of sulfur containing purine nucleosides on immunological reaction in mice part 1 immuno suppressive effect of several alkyl thio purines aralkyl thio purines and thio cyanato purines and their ribo nucleosides. Japanese Journal of Experimental Medicine 43(5): 369-375

Tidd, D.M.; Dedhar, S., 1978: Specific and sensitive combined high performance liquid chromatographic flow fluorometric assay for intra cellular 6 thio guanine nucleotide metabolites of 6 mercapto purine and 6 thio guanine. A new non-radioisotopic technique is described for measuring rates of intracellular formation by human leukemic blasts of 6-thioguanine nucleotide metabolites, obligatory intermediates in the antineoplastic action of both 6-mercaptopurine and 6-th...

Brown R.S.; Kelley W.N.; Seegmiller J.E.; Carbone P.P., 1968: The effect of thio purines upon lymphocytes lacking enz hypo xanthine guanine phosphoribosyl transferase abstract 6 mercapto purine thio inosinic acid human. Clinical Research 16(4): 549

Hughes N.A., 1973: 5 thio d ribo pyranose part 3 conformational equilibria in the methyl d ribo pyranosides their 1 thio 5 thio and 1 5 di thio analogues and the related tri acetates. Carbohydrate Research: 97-105

Lee W.W.; Martinez A.P.; Blackford R.W.; Bartuska V.J.; Reist E.J.; Goodman L., 1971: Xylo puranosyl thio guanine arabino furanosyl thio guanine and related nucleosides derived from 2 acetamido 6 chloro purine. Journal of Medicinal Chemistry 14(9): 819-823

Van Hoof F.; Heyndrickx A., 1973: Thin layer chromatographic spectrophoto fluorometric methods for the determination of di thio carbamates and thio carbamates after hydrolysis and coupling with 4 chloro 7 nitro benz 2 1 3 oxadiazole. Mededelingen van de Faculteit Landbouwwetenschappen Universiteit Gent 38(3): 911-916

Sidwell R.W.; Arnett G.; Dixon G.J.; Schabel F.M.Jr, 1969: Purine analogues as potential anti cytomegalovirus agents abstract neopl wi 38 cells 6 thio guanine 6 thio guanosine 9 beta d ribofuranosyl 9 h purine 6 thio purine 6 propylthiol 2 amino 6 1 methyl 4 nitroimidazol 5 yl thio purine 2 amino 1 methyl purine 6 1h thione purine 6 carboxaldehyde thio semi carbazone 9 beta d arabinofuranosyl adenine anti viral. Bacteriological Proceedings 69: 191

Al-Masoudi, N.A.L.; Hughes, N.A., 1987: 5 thiopyranoses part 11. isopropylidene acetals of 5 thio d glucose 5 thio d allose and 5 thio d altrose and some of their methyl glycosides. 5-Thio-D-glucose (9) reacts with acetone in the presence of an acid catalyst to give 1,2-O-5,6-S,O-diisopropylidene-5-thio-.alpha.-D-glucofuranose (10). 5-Thio-D-altrose (37) similarly gives a 1,2:5,6-diacetal (39) but 5-thio-D-allose (27) affords...

Matolcsy G.; Hamran M.; Bordas B., 1973: Synthesis and anti fungal properties of di thio carboxylic acid derivatives part 3 di methylaminomethyl di thio carboxylates and beta di thio carbamates. Acta Phytopathologica Academiae Scientiarum Hungaricae 8(1-2): 255-259

Vassilev G.N.; Spasovska N.H.; Spasov A.V., 1981: Synthesis and cyto kinin activity of 6 hydrazino purine and 6 alkyl thio semi carbazido purines or aryl thio semi carbazido purines. Dokladi na B"lgarskata Akademiya na Naukite 34(2): 253-256