EurekaMag.com logo
+ Site Statistics
References:
48,252,460
Abstracts:
22,798,453
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Spectrophotometric determination of menadione and menadione sodium bisulfite in pharmaceutical preparations


, : Spectrophotometric determination of menadione and menadione sodium bisulfite in pharmaceutical preparations. International Journal of Pharmaceutics (Kidlington) 39(1-2): 137-140

A simple, selective and sensitive spectrophotometric method is described by the determination of menadione (or menadione sodium bisulfite) in bulk samples and pharmaceutical preparations. The method is based on the reaction of its reduction product with 3-methyl-2-benzothiazolinone hydrozone (MBTH) in the presence of ferric chloride whereby intense blue colour with maximum absorption at 650-670 nm is developed. The reaction is sensitive enough to permit the determination of 0.6-7.5 .mu.g menadione/ml with an average recovery of 99% and a standard deviation of 1.7%. There is no interference from other vitamins or from any common pharmaceutical diluents and additives.

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006460442

DOI: 10.1016/0378-5173(87)90208-0

Download PDF Full Text: Spectrophotometric determination of menadione and menadione sodium bisulfite in pharmaceutical preparations


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Petroff, O.A.; Rothman, D.L.; Behar, K.L.; Hyder, F.; Mattson, R.H., 1999: Effects of valproate and other antiepileptic drugs on brain glutamate, glutamine, and GABA in patients with refractory complex partial seizures. Preclinical studies suggested valproate increased brain gamma-aminobutyric acid (GABA) with no major effects on brain glutamate or glutamine. Valproate increased human cerebrospinal fluid GABA and glutamine in some studies; others reported no effe...

Jia JianZhang; Wang DengFeng; Wang ZhiZhong, 1997: Research on the self-excited vibration in wheeled vehicle powertrain (Part IV) Analysis of factors influencing vehicle stability and measures to control the self-excited vibration. The influences of structural factors on vehicle stability were studied, and the results showed that increasing the torsional damping of the transmission axle and half-axle can significantly increase vehicle stability. External factors influencing...

Ardehali, M.; Darakhshan, H., 1975: Isolation and characterization of clostridium chauvoei strains isolated from cases of blackleg in cattle in iran. Strains of C. chauvoei (15) were isolated from cases of blackleg in cattle in Iran. Isolation and identification were achieved using the fluorescent antibody technique. Hemolytic activity, toxicity and sensitivity of the isolates to several antibi...

Pandurski, F.; Slavov, N., 1986: Spontaneous and induced fetal diuresis. Akusherstvo i Ginekologiia 25(2): 59-61

Komada, F.; Nishiguchi, K.; Tanigawara, Y.; Wu, X.Y.; Iwakawa, S.; Okumura, K., 1996: Effect of transfection with a superoxide dismutase expression plasmid on xanthine/xanthine oxidase-induced cytotoxicity in cultured rat lung cells. We inserted human Cu, Zn-superoxide dismutase (hSOD) cDNA into the eukaryotic expression plasmid (pRc/CMV) under the control of the cytomegalovirus promoter. The hSOD expression plasmid (pRc/CMV-SOD) was transfected in L2 cells by mean of lipofect...

Liu, X-Hai.; Chen, P-Quan.; Wang, B-Lei.; Dong, W-Li.; Li, Y-Hong.; Xie, X-Qiao.; Li, Z-Ming., 2010: High throughput receptor-based virtual screening under ZINC database, synthesis, and biological evaluation of ketol-acid reductoisomerase inhibitors. Ketol-acid reductoisomerase (KARI; EC 1.1.1.86) catalyzes the second common step in branched-chain amino acid biosynthesis. This enzyme is an important target for drug design. Based on the crystal structure of ketol-acid reductoisomerase/N-hydroxy...

Szabó, J.; Beck, Z.; Csomán, E.; Liu, X.; Andrikó, I.; Kiss, J.; Bácsi, A.; Ebbesen, P.; Tóth, F.D., 1999: Differential patterns of interaction between HIV type 1 and HTLV type I in monocyte-derived macrophages cultured in vitro: implications for in vivo coinfection with HIV type 1 and HTLV type I. The interaction between human immunodeficiency virus type 1 (HIV-1) and human T cell leukemia-lymphoma virus type I (HTLV-I) has generated substantial interest. However, there is disagreement on the in vivo consequences of the double infection. We...

Schofield, P.J.; Comerford, M.J.; de Jongh, K.S., 1983: Comparative inhibition profiles of human brain and mouse liver L-hexonate dehydrogenase. The inhibition profiles of mouse liver and human brain hexonate dehydrogenase were compared. In general, the pattern for fluoride, lithium, phenobarbital, hydroxylamine and iodoacetate inhibition is similar. Contrary to previous findings, the mous...

Swayze, J.S.; Hoffman, D.B.; Stefanchik, D.; Goldin, M.A.; Nobis, R.H., 2003: Anastomosis device having improved tissue presentation. In accordance with the present invention there is provided a surgical device for presenting a first hollow organ and a second hollow organ for creation a passageway therebetween. The surgical device includes a member, an upper pin for entering a f...

Bonilla, E.; Schotland, D.L.; Di-Mauro, S.; Lee, C.P., 1977: Lufts disease an electron cytochemical study. Conventional electron microscopic studies of skeletal muscle from a 2nd patient with Luft's disease revealed the presence of subsarcolemmal and intermyofibrillar collections of large mitochondria containing packed cristae, round osmiophilic i...