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Spectorphotometric determination of methisazone and its extraction from mixtures


Spectorphotometric determination of methisazone and its extraction from mixtures



Farmatsevtychnyi Zhurnal 1975(2): 73-75



ISSN/ISBN: 0367-3057

PMID: 1140365

This drug is used for the treatment of herpes simplex infections was distributed between chloroform, ether or benzene and various buffers of pH 2.0-11. Ether removed 93% of the drug at pH 6 while chloroform removed 93% of the drug at all the pH below 6. The concentration was determined by the UV spectrum at the maxima in hexane: 241, 274 and 365 nm where .**GRAPHIC**. [extinction coefficient] was 539, 510 and 868. These data are important for determining the drug in biological material.

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