EurekaMag.com logo
+ Site Statistics
References:
53,517,315
Abstracts:
29,339,501
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Sperm penetration assay: useful test in evaluation of male fertility



Sperm penetration assay: useful test in evaluation of male fertility



Obstetrics and Gynecology 57(5): 620-623



The recently developed sperm penetration assay (SPA) tests the functional capacity of sperm. It is based upon the ability of in vitro capacitated human spermatozoa to penetrate zona-free hamster eggs in vitro. The SPA was superior to seminal fluid analysis in predicting both fertility and infertility; in the prediction of infertility, the difference was highly significant. Data further indicated that fertility in the male may not remain constant with the passage of time. The SPA would appear to have wide application both clinically and experimentally.

(PDF 0-2 workdays service: $29.90)

Accession: 006461834

Download citation: RISBibTeXText

PMID: 7219910



Related references

The correlation between the zona free hamster egg penetration assay and the other parameters of the sperm the value of this test in investigating male fertility. Journal de Gynecologie Obstetrique et biologie de la Reproduction 18(6): 729-734, 1989

Destruction of protamine in human sperm inhibits sperm binding and penetration in the zona-free hamster penetration test but increases sperm head decondensation and male pronuclear formation in the hamster-ICSI assay. Journal of Assisted Reproduction & Genetics 16(3): 128-132, March, 1999

Sperm penetration assay assessment of male fertility. Journal Of Andrologyuppl: 138-P, 1985

Hyaluronan binding assay (HBA) vs. sperm penetration assay (SPA): Can HBA replace the SPA test in male partner screening before in vitro fertilization?. Journal of Experimental & Clinical Assisted Reproduction 7(): 2-2, 2010

Evaluation of tiger fertility by the sperm penetration assay. Unknown, 1987

Occurrence of the interference of sperm-associated antibodies on sperm fertilizing ability as evaluated by the sperm-zona pellucida binding test and by the TEST-yolk buffer enhanced sperm penetration assay. International Journal Of Andrology. 20(suppl. 1): 51, 1997

Sperm penetration assay in evaluation for male infertility. Japanese Journal of Fertility & Sterility 36(3): 168-173, 1991

Fundamental examination on application of the zona free hamster egg sperm penetration test for male rat fertility testing. Congenital Anomalies 37(3): 310, Sept, 1997

Evaluation of male fertility by testing sperm penetration into ova of the Syrian hamster (Mesocricetus auratus). Ceskoslovenska Gynekologie 48(10): 731-736, 1983

Correlation between semen analysis sperm penetration assay and immunobead test sperm antibody assay. Journal of Urology 141(4 PART 2): 442A, 1989

Novel parameters of human sperm hypoosmotic swelling test and their correlation to standard spermatogram, total motile sperm fraction, and sperm penetration assay. Fertility and Sterility 59(6): 1276-1279, 1993

A new subdivision of the human sperm hypoosmotic swelling test and its correlation to standard spermatogram, total motile sperm fraction and sperm penetration assay. Human Reproduction (Oxford) 7(SUPPL 2): 92-93, 1992

Evaluation of the heparin-induced sperm chromatin instability, and its correlates with the sperm penetration assay and sperm motility, concentration, HOS and morphology. Journal of Andrology (SUPPL ): 39, 1998