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Structure carcinogenic activity relationships in the benz a anthracene series 1 7 12 tri methyl benz a anthracene and 2 7 12 tri methyl benz a anthracene



Structure carcinogenic activity relationships in the benz a anthracene series 1 7 12 tri methyl benz a anthracene and 2 7 12 tri methyl benz a anthracene



Journal of Medicinal Chemistry 20(1): 179-181



The syntheses of 1,7,12-trimethyl- and 2,7,12-trimethylbenz[a]anthracenes are described. The lack of carcinogenic activity of these compounds is discussed in relationship to the carcinogenic activity of other substituted benz[a]anthracenes.

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