+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Studies on immunoglobulin receptors and the action of immunoglobulin g antibody on basophils in bronchial asthmatics i. the role of immunoglobulin g antibody in intractable asthma



Studies on immunoglobulin receptors and the action of immunoglobulin g antibody on basophils in bronchial asthmatics i. the role of immunoglobulin g antibody in intractable asthma



Okayama Igakkai Zasshi 98(5-6): 525-536



To clarify the action of IgG antibody on basophils in intractable asthmatics, morphological changes, density and redistribution of IgG antibodies on basophils were observed by immunoscanning electron microscopy. Pear-shaped basophils appeared more frequently in severe asthmatics than in non-severe asthmatics when anti-IgG was added. The density of IgG antibodies bound to basophils was significantly higher in severe, but steroid-independent, asthmatics than in non-severe asthmatics and in steroid-dependent asthmatics (p < 0.001). Cap and patch formations of IgG receptors on the cell were more frequent in severe asthmatics than in non-severe asthmatics. These findings suggest that the reactivity of basophils mediated by IgG antibodies is enhanced according to the severity of asthma, indicating that IgG antibodies act as anaphylactic antibodies in severe asthmatics, although IgG antibodies bound to the cell decrease during long-term steroid therapy.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 006508289

Download citation: RISBibTeXText


Related references

Studies on immunoglobulin receptors and the action of immunoglobulin g antibody on basophils in bronchial asthmatics ii. the role of immunoglobulin g antibody in hyposensitization therapy. Okayama Igakkai Zasshi 98(5-6): 537-548, 1986

Kinetics of specific immunoglobulin a immunoglobulin d immunoglobulin e immunoglobulin g and immunoglobulin m antibody responses in rubella. Journal of Medical Virology 16(1): 1-10, 1985

Role of immunoglobulin E and immunoglobulin E receptors in bronchial asthma. Journal of Allergy and Clinical Immunology 68(1): 5-14, 1981

Monoclonal antibodies against goldfish immunoglobulin Application to the quantification of immunoglobulin and antibody-secreting cells by ELISPOT and seric immunoglobulin and antibody levels by ELISA in carp. Veterinary Research 25(5): 458-467, 1994

Monoclonal antibodies against goldfish (Carassius auratus) immunoglobulin: application to the quantification of immunoglobulin and antibody-secreting cells by ELISPOT and seric immunoglobulin and antibody levels by ELISA in carp (Cyprinus carpio). Veterinary Research 25(5): 458-467, 1994

Measurement of primary in vivo immunoglobulin m antibody and immunoglobulin g antibody response to keyhole limpet hemocyanin in humans implications of pre immune immunoglobulin m binding in antigen specific elisa enzyme linked immunosorbent assay. Journal of Immunological Methods 74(2): 241-252, 1984

Changes in immunoglobulin g immunoglobulin a and immunoglobulin m in children with bronchial asthma with respect to the clinical course and the corticosteroid treatment of the disease. Pediatria Polska 62(5): 296-302, 1987

Immunoglobulin g 2 antibodies block immunoglobulin e antibody induced asthma in guinea pigs. International Archives of Allergy & Applied Immunology 80(1): 76-80, 1986

Quantitative action of B lymphocytes and serum immunoglobulin in children with bronchial asthma following a single therapeutic substitution of immunoglobulin A concentrate. Zeitschrift für Erkrankungen der Atmungsorgane 159(3): 259-266, 1982

Impaired immunoglobulin g 2 anti pneumococcal antibody responses in patients with recurrent infection and normal immunoglobulin g 2 levels but no immunoglobulin a. Clinical & Experimental Immunology 65(2): 427-433, 1986

Opsonic cytotoxic precipitating blocking of bacterial adherence and other activities of monoclonal immunoglobulin e antibody compared with immunoglobulin a and immunoglobulin m. Immunology 53(3): 427-434, 1984

High dietary vitamin a serum immunoglobulin g immunoglobulin m and immunoglobulin a and antileishmania antibody levels in balb c and nude mice. Federation Proceedings 45(3): 710, 1986

Elisa for mumps immunoglobulin m antibody comparison of immunoglobulin m capture and indirect immunoglobulin m assay. Journal of Virological Methods 12(3-4): 303-312, 1985

Home therapy with subcutaneous anti-immunoglobulin-E antibody omalizumab in 25 patients with immunoglobulin-E-mediated (allergic) asthma. Journal of Asthma 44(3): 195-196, 2007

Immunoglobulin e fc receptor positive lymphocytes and regulation of the immunoglobulin e antibody system v. preliminary physicochemical characterization of the t cell selective immunoglobulin e induced regulant eir t. Journal of Immunology 137(8): 2599-2610, 1986