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Studies on supravital observation of basophils in bronchial asthma in immunological reaction part 1 changes of migration velocity of basophils by addition of anti immuno globulin



Studies on supravital observation of basophils in bronchial asthma in immunological reaction part 1 changes of migration velocity of basophils by addition of anti immuno globulin



Okayama Igakkai Zasshi 87(11-12): 955-961



Changes of migration velocity of peripheral blood basophils by addition of anti-IgE [immunoglobulin E] or anti-IgG were observed in 13 asthma patients, including 5 with high level IgE asthma, 5 with low level IgE asthma and 3 with buckwheat asthma. Basophils from high level IgE asthma cases showed increased migration velocity upon addition of anti-IgE. Upon addition of anti-IgG, the basophils showed no change in migration velocity. Basophils from low level IgE intractable asthma patients showed increased migration velocity upon addition of anti-IgG, but not anti-IgE. Antigen exposed basophils from buckwheat asthma cases showed similar changes as seen in high level IgE cases.

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