Studies on the antigenic relationship between grass and rye pollens by skin test radio allergo sorbent test and radio allergo sorbent test inhibition test in patients with pollinosis
Kalveram, K.J.; Forck, G.
Archiv fuer Dermatologische Forschung 260(1): 17-28
1977
Accession: 006513464
Skin tests on patients suffering from pollinosis frequently suggest an antigenic relationship between various grass and rye pollens. This problem was further studied using the RAST [radioallergosorbent test] and RAST inhibition test. The tests were performed with commercial grass pollen discs as well as with self-prepared discs labeled with rye pollens and a combination of various grass antigens. Good agreement was found between self-made and commercial (single antigen) grass pollen discs (95.9%). RAST and skin test correlated also extremely well (92.3%). Mutual inhibition between grass and rye pollens was measured by RAST inhibition test using self-prepared discs. A significant antigenic relationship was found between grass and rye pollens. The antibody pattern varies and contains grass-specific antibodies.