Studies on the chromosomal rearrangements induced by the male recombination factor 31.1 mrf in drosophila melanogaster

Yannopoulos, G.; Zacharopoulou, A.

Mutation Research 73(1): 81-92


ISSN/ISBN: 1386-1964
DOI: 10.1016/0027-5107(80)90137-2
Accession: 006514556

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A cytological analysis was carried out on the salivary gland chromosomes of 3rd instar larvae deriving from appropriate crosses of the 31.1/CyL4 strain with the dp b cn bw and dp b cn bw; ve strains. The 31.1 MRF induced chromosomal rearrangements in both male and female germ cells. The aberrations that occurred in the male germ cells were of 3 types, inversions, duplications and deficiencies, whereas those that occurred in the female germ cells were of all types. The distributions of the breakpoints among the 4 major autosomal arms between the 1F2 and 2AF2 larvae were different. The total distribution of the breakpoints along the polytene chromosomes showed that the factor induced breaks in all major chromosomes (X, II, III) and that 51.81% of them occurred in sites showing late replication and/or ectopic pairing. A relationship existed between the frequencies of the 2nd chromosomal aberrations and male recombination. A comparison of the breakpoints induced by the factor was made with those found in the rare endemic inversions of the same natural population from which the 31.1 MRF was isolated. The possibility that the factor acts in the natural population is discussed.