Studies on the establishment and some biological characteristics of cultured human liver cancer cell lines their growth functional and morphological characteristics and temperature sensitivities
Jikeikai Medical Journal 32(2): 289-316
ISSN/ISBN: 0021-6968 Accession: 006516372
Three cell lines of human hepatocellular carcinomas, a bile duct and a gallbladder carcinoma, were successfully established in vitro. Their growth, chromosomes, functional and morphological characteristics were examined. The temperature sensitivity of the cultured human hepatocellular carcinoma cells was studied using a temperature gradient incubator. Inhibition of the cell proliferation and of protein synthesis and disturbance of mitosis were observed in hyperthermia. The findings show the potency of hyperthermia as a clinical therapy of liver cancer.