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Studies on the etiology and therapy of sjogrens syndrome 1. erythro phagocytic activity of peripheral blood monocytes in patients with sjogrens syndrome



Studies on the etiology and therapy of sjogrens syndrome 1. erythro phagocytic activity of peripheral blood monocytes in patients with sjogrens syndrome



Okayama Igakkai Zasshi 94(1-2): 25-34



The erythrophagocytic activity of peripheral blood monocytes in patients with Sjogren's syndrome (SjS) was investigated by using 51Cr-labeled SRBC [sheep erythrocyte] sensitized with anti-SRBC antibody (IgG). The phagocytic activity of monocytes in patients with SjS alone was similar to that in healthy adults. The phagocytic activity of monocytes in patients with SjS associated with systemic lupus erythematosus or rheumatoid arthritis was lower than that in healthy adults. There was no significant correlation between phagocytic activity and several clinical parameters such as serum rheumatoid factor, erythrocyte sedimentation rate, serum complement level or the doses of prednisolone administered.

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