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Studies on the structure of amino acid glucosamine conjugate isolated from blood plasma of rats with guerin carcinoma


Eksperimental'naya Onkologiya 9(5): 78-80
Studies on the structure of amino acid glucosamine conjugate isolated from blood plasma of rats with guerin carcinoma
The conjugate of amino acids and glucosamine (glycamine) was purified to homogeneity from blood plasma of rats with Guerin carcinoma. The NH2-groups of amino acids in the glycamine are free. Amino acids are linked to glucosamine via carboxyl groups. 8 amino acid residues were identified in the glycamine molecule (Glu-2, Ser-2, Gly-3, Lys-1). Spatial atomic-molecular model of the glycamine molecule was developed. Two glucosamine molecules are linked to diaminosaccharide via (1-4)-bond, 8 amino acid molecules are linked to diaminosaccharide via 6 ester and 2 pseudopeptide bonds.


Accession: 006522089



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