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Studies on the turnover of endogenous cathodal trypsinogen in man






European Journal of Clinical Investigation 8(6): 379-382

Studies on the turnover of endogenous cathodal trypsinogen in man

The concentration in serum of cathodal trypsinogen was studied in clinical and experimental situations. The concentration correlated with pancreatic amylase activity. Low levels were found in patients with malabsorption due to exocrine pancreatic insufficiency. The concentration rose after endoscopic retrograde cholangiopancreatographic examinations (ERCP). After ERCP no trypsin was detected bound to protease inhibitors, as is generally found in acute pancreatitis. The trypsinogen concentration in serum also rose in renal failure, indicating a renal elimination route for the endogenous trypsinogen.

Accession: 006522703

PMID: 105910

DOI: 10.1111/j.1365-2362.1978.tb00868.x

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