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Superiority of supine bicycle over isometric handgrip exercise in the assessment of ischemic heart disease an evaluation of left ventricular ejection fraction response using radionuclide angiography



Superiority of supine bicycle over isometric handgrip exercise in the assessment of ischemic heart disease an evaluation of left ventricular ejection fraction response using radionuclide angiography



Clinical Cardiology 7(10): 547-553



Left ventricular ejection fraction (LVEF) response to supine bicycle and isometric handgrip exercise was evaluated in 15 patients with documented coronary artery disease (CAD) and stress-induced ischemia using radionuclide angiography. The patients were divided into 2 groups: group I (n = 7) with single-vessel disease and group II (n = 8) with multiple-vessel disease, including 3 with left main artery disease. The studies were repeated 18 days later at similar external workloads to assess reproducibility of both tests. LVEF response to bicycle exercise was different for the 2 groups. The change in LVEF from rest to peak exercise was + 0.04 .+-. 0.02 for Group I and -0.07 .+-. 0.04 for group II (P < 0.001). LVEP response to isometric handgrip exercise was not different between the 2 groups. The change from rest to end of handgrip exercise was -0.02 + 0.02 for group I and -0.05 .+-. 0.02 for group II. The reproducibility of LVEF response to bicycle exercise at similar workloads on day 1 and day 19 was good (r = 0.85), while it was poor for isometric handgrip testing (r = 0.67). Radionuclide angiographic measurement of LVEF response to supine bicycle exercise testing is superior to LVEF response to isometric handgrip testing in the evaluation of patients with CAD.

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Accession: 006542786

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PMID: 6488599

DOI: 10.1002/clc.4960071006


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