EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Supraependymal nerve fibers in human brain correlative transmission and scanning electron microscopical and fluorescence histochemical studies


Neuroscience 5(8): 1489-1502
Supraependymal nerve fibers in human brain correlative transmission and scanning electron microscopical and fluorescence histochemical studies
Supraependymal, varicose nerve fibers were observed in human post-mortem brain when ventricle surfaces were examined by transmission and scanning electron microscopy. Transmission electron microscopy revealed the presence of numerous profiles of nerve terminals, containing small electron-lucent vesicles and large dense-cored vesicles and axons with their characteristic neurotubules. Occasionally desmosome-like junctions were found between the nerve terminals and the adjacent ependymal cells. Scanning electron microscopy demonstrated the topographical distribution of varicose nerve fibers traversing among clusters of cilia and numerous microvilli on the ventricle surface. These nerve fibers, which were most frequently observed in the interventricular foramen, often coursed in bundles. In 1 of 5 cases, a discrete formaldehyde-induced fluorescence typical of 5-hydroxytryptamine (yellow color and rapid fading upon violet-blue irradiation) was observed on the floor of the 4th ventricle. Supraependymal nerve fibers in human brain are probably identical to similar nerves previously characterized as serotoninergic in rat brain and occurring in several other mammalian brains.


Accession: 006546041

PMID: 7402482



Related references

Supraependymal nerve fibres in human brain: correlative transmission and scanning electron microscopical and fluorencence histochemical studies. Neuroscience 5(8): 1489-1502, 1980

The rat epithalamus. I. Correlative scanning-transmission electron microscopy of supraependymal nerves. Cell and Tissue Research 182(1): 1-16, 1977

Demonstration of supraependymal 5 hydroxy tryptamine nerve fibers in human brain and their immuno histochemical identification in rat brain. Journal de Physiologie (Paris) 77(2-3): 219-224, 1981

The rat epithalamus part 1 correlative scanning transmission electron microscopy of supraependymal nerves. Cell and Tissue Research 182(1): 1-16, 1977

Supraependymal neurons overlying the periventricular region of the third ventricle of the guinea pig: a correlative scanning--transmission electron microscopic study. Anatomical Record 192(3): 441-457, 1978

Correlative scanning electron microscopy and transmission electron microscopy analysis of the formation of supraependymal cells following ovariectomy in the immature female rat. Anatomical Record 199(3): 195A, 1981

Supraependymal neurons overlying the peri ventricular region of the 3rd ventricle of the guinea pig a correlative scanning transmission electron microscopic study. Anatomical Record 192(3): 441-458, 1978

Correlative scanning and transmission electron microscopy of the supraependymal neuronal complex in the hamster third ventricle following radiofrequency lesions of the midbrain raphe nuclei. Society for Neuroscience Abstracts 16(2): 1033, 1990

Immuno histochemical and electron microscopical studies on serotonin containing nerve fibers in the pineal organ of the rat. Biomedical Research (Tokyo) 4(3): 261-270, 1983

Presence of nerve fibers in the human umbilical cord--an electron microscopical histochemical proof. Nihon Sanka Fujinka Gakkai Zasshi 40(11): 1775-1776, 1988