EurekaMag.com logo
+ Site Statistics
References:
53,214,146
Abstracts:
29,074,682
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Sural nerve biopsies from workers with a history of chronic exposure to organic solvents and from normal control cases. Morphometric and ultrastructural studies






Acta Neuropathologica 62(1-2): 73-86

Sural nerve biopsies from workers with a history of chronic exposure to organic solvents and from normal control cases. Morphometric and ultrastructural studies

An ultrastructural and morphometric study was performed on sural nerve biopsies of four industrial spray painters (35-59 years) and 11 controls (6-64 years). No difference could be shown in spray painters and age-matched controls as to the number of myelinated nerve fibres per area, their size distribution, variation of internodal length along single nerve fibres or the ratio between the number of myelin lamellae and the axon circumference. There was marked scattering of the two latter parameters in older exposed and and control individuals. The distribution of NADH2-tetrazolium reductase activity was similar in exposed and control cases. The general ultrastructural appearance of nodal-paranodal regions in controls conformed with that noted in experimental animals. The overall ultrastructural organization and age-related changes of nerves of exposed cases were similar to those of control cases except for a presence of paranodal axonal mitochondria which contained glycogen-like particles in exposed cases. In one exposed case abundant dispersed or clustered glycogen-like particles were seen in the paranodal axoplasm. These findings are suggested to be an effect of chronic exposure to organic solvent vapours. Ageing seems, however, to have a much greater impact on the morphology of the sural nerve fibre than occupational exposure to organic solvent.

(PDF 0-2 workdays service: $29.90)

Accession: 006546338

PMID: 6659879



Related references

Sural nerve biopsies from workers chronically exposed to organic solvents and from control cases. Neuropathology & Applied Neurobiology 10(4): 308-309, 1984

Ultrastructural morphometric analysis of human sural nerve biopsies. Diabetic Medicine 13(7): 675-676, 1996

Hereditary motor and sensory neuropathy of demyelinating and remyelinating type in children. Ultrastructural and morphometric studies on sural nerve biopsy specimens from ten sporadic cases. Acta Neuropathologica 65(1): 1-9, 1984

Hereditary motor and sensory neuropathy of demyelinating and remyelinating type in children ultrastructural and morphometric studies on sural nerve biopsy specimens from 10 sporadic cases. Acta Neuropathologica 65(1): 1-9, 1984

Peripheral nerve findings in hereditary coproporphyria. Light and ultrastructural studies in two sural nerve biopsies. Acta Neuropathologica 63(2): 96-107, 1984

Ultrastructural morphometric studies on regeneration of the lateral sural cutaneous nerve in the white rat after transection of the sciatic nerve. Scandinavian Journal of Plastic and Reconstructive Surgery. Supplementum 20: 1-126, 1984

Peripheral nerve findings in hereditary copro porphyria light microscopic and ultrastructural studies in 2 sural nerve biopsies. Acta Neuropathologica 63(2): 96-107, 1984

Ultrastructural morphometric studies on regeneration of the lateral sural cutaneous nerve in the white rat after transection of the sciatic nerve 2. regeneration after nerve suture and nerve grafting. Scandinavian Journal of Plastic and Reconstructive Surgery Supplementum 20: 27-64, 1984

Health control of workers using organic solvents part 4 relation between concentration of organic solvents in the air and urinary glycine conjugates after short time exposure. Okayama Igakkai Zasshi 90(11-12): 1473-1478, 1978

Skin and sural nerve biopsies: ultrastructural findings in the first genetically confirmed cases of CADASIL in Serbia. Ultrastructural Pathology 36(5): 325-335, 2013