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Surface antigens of rat liver epithelial cells grown in medium containing fetal bovine serum


British Journal of Cancer 38(3): 456-460
Surface antigens of rat liver epithelial cells grown in medium containing fetal bovine serum
Cultured rat liver cells induced a strong antibody response in syngeneic rats, directed against fetal calf serum components which were incorporated into the liver cell surface from the cell-culture medium. This antibody could be removed by absorption with liver cells or glutaraldehyde-fixed fetal calf serum. The antigenic cross-reactivity observed in earlier studies with cultured cells treated with carcinogens may have been due to this fetal calf serum component.


Accession: 006546548

PMID: 81676



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