EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Sympathectomy inhibits growth of a murine plasmacytoma tumor


, : Sympathectomy inhibits growth of a murine plasmacytoma tumor. Journal of the Autonomic Nervous System 13(2): 149-160

The effects of 6-hydroxydopamine (6-OHDA), N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) and anti-nerve growth factor (anti-NGF) on the development and growth of a tumor of non-neuronal origin were studied in mice. Murine LPC-1 plasmacytoma cells were grown either s.c. as solid tumors in the hindleg or i.p. in ascitic form. Growth of s.c. tumors was monitored by caliper measurements of the hindleg at the site of tumor cell inoculation; growth of ascitic tumors was followed by electrophoretic determination in plasma of the tumor associated protein IgG2a.kappa., M component. Adult mice were treated with 6-OHDA or DSP-4 6 h prior to tumor cell implantation; newborn mice were treated with anti-NGF and tumor cells were given 9 wk later. Both chemical- and immunosympathectomy significantly altered the growth pattern of solid and ascitic tumors (P < 0.0001). The effect of sympathectomy on the growth of solid tumors was most pronounced during the early phase of tumor growth. The effect of each drug treatment on tumor growth was not due to direct cytotoxic actions of the agents employed on tumor cells but the result of impairment of sympathetic functions. The sympathetic nervous system may play a role in tumor growth.

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006555705

PMID: 3926856

DOI: 10.1016/0165-1838(85)90031-1

PDF Full Text: Sympathectomy inhibits growth of a murine plasmacytoma tumor


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Fransoo, R.R.; Roos, N.P.; Martens, P.J.; Heaman, M.; Levin, B.; Chateau, D., 2008: How health status affects progress and performance in school: a population-based study. To assess the effects of health status at birth and health status in the preschool years on educational outcomes to age 9 in a population-based birth cohort. Administrative data were used to follow all children born to Winnipeg mothers in 1990, an...

Saetae, D.; Suntornsuk, W., 2011: Toxic compound, anti-nutritional factors and functional properties of protein isolated from detoxified Jatropha curcas seed cake. Jatropha curcas is a multipurpose tree, which has potential as an alternative source for biodiesel. All of its parts can also be used for human food, animal feed, fertilizer, fuel and traditional medicine. J. curcas seed cake is a low-value by-pro...

Leung, K.K.; Finlay, J.; Silvius, J.L.; Koehn, S.; McCleary, L.; Cohen, C.A.; Hum, S.; Garcia, L.; Dalziel, W.; Emerson, V.F.; Pimlott, N.J.G.; Persaud, M.; Kozak, J.; Drummond, N., 2011: Pathways to diagnosis: exploring the experiences of problem recognition and obtaining a dementia diagnosis among Anglo-Canadians. Increasing evidence suggests that early diagnosis and management of dementia-related symptoms may improve the quality of life for patients and their families. However, individuals may wait from 1-3 years from the onset of symptoms before receiving...

Gosswald, K., 1942: Artificial multiplication of the red forest ant.. The author considers that the red forest ant (Formica rufa L.) is an important factor in the prevention of outbreaks of forest insects in Germany. Attempts to breed this insect must be based on knowledge of its races, which differ in their ecology...

Sente, T.; Gevaert, A.; Van Berendoncks, A.; Vrints, C.J.; Hoymans, V.Y., 2016: The evolving role of adiponectin as an additive biomarker in HFrEF. NlmCategory="UNASSIGNED">Heart failure (HF) is a growing health problem. Despite improved management and outcome, the number of patients with HF is expected to keep rising in the following years. In recent research, adiponectin was sh...

Low, G.C.; Franklin, R.H., 1932: New antimony preparations in treatment of Mediterranean leishmaniasis and Japanese (or eastern) schistosomiasis. A case of Schistosoma japonicum, in an Englishman, was successfully treated by intramuscular injections of neo-antimosan. Ten injections were given in 13 days; 8 doses of 5 c.cm. were given after two initial doses of 1.5 c.cm. and 3.5 c.cm.

Lee, G.; Raleigh, E.D., 1983: A half-way house for the new graduate. Nursing Management 14(1): 43-45

Sansonetti, P.J., 1999: Pathogenesis of shigellosis: from molecular and cellular biology of epithelial cell invasion to tissue inflammation and vaccine development. Japanese Journal of Medical Science & Biology 51 Suppl: S69-S80

Rossi, C.A.; Clabattoni, G., 1951: Absorption spectrum of vitamin B1 hydroiodide. The hydroiodide of vitamin B1 was purified by crystallization from water containing a little hydriodic acid. It had m.p. 234 degrees to 235 degrees C. with decomposition. The absorption spectrum was determined with a Beckman specirophotometer in p...

Gilbert, R.; Fischman, D.A.; Mikawa, T., 1994: Role of myosin binding protein C in myofibril assembly. FASEB Journal 8(4-5): A178