+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Synovial fluid lactic acid measurement in the diagnosis and management of septic arthritis



Synovial fluid lactic acid measurement in the diagnosis and management of septic arthritis



Journal of Clinical Pathology 35(4): 390-394



An improved method of lactic acid estimation by gas liquid chromatography (GLC) is described. Synovial fluid lactic acid estimation was performed on 52 patients (15 with septic arthritis and 37 with non-septic arthropathies) and compared to routine microbiological methods and white cell counts. Lactic acid was found to be a useful and rapid test for differentiating between septic and non-septic arthritis being markedly raised (greater than 12 mmol/l) in all the septic joints. Raised lactic acid concentrations were of particular diagnostic value in patients in whom antibiotic therapy had commenced before joint aspiration. The results of lactic acid estimation on sequential samples were helpful in assessing the response of septic arthritis to treatment.

(PDF emailed within 0-6 h: $19.90)

Accession: 006559218

Download citation: RISBibTeXText

PMID: 7076866

DOI: 10.1136/jcp.35.4.390


Related references

Synovial fluid lactic acid in septic arthritis. New Zealand Medical Journal 93(678): 115-117, 1981

Synovial fluid lactic acid in septic and nonseptic arthritis. Arthritis & Rheumatism 26(12): 1499-1505, 1983

Synovial fluid lactic acid levels in septic arthritis. Pathology 13(1): 69-71, 1981

Synovial fluid lactic acid. A diagnostic aid in septic arthritis. Arthritis and Rheumatism 21(7): 774-779, 1978

Gas-liquid chromatographic analysis of synovial fluid. Succinic acid and lactic acid as markers for septic arthritis. Arthritis and Rheumatism 25(8): 947-953, 1982

Synovial fluid analysis by gas liquid chromatography succinic acid and lactic acid as markers for septic arthritis. Arthritis & Rheumatism 24(4 SUPPL): S90, 1981

Serial synovial fluid analysis by gas liquid chromatography correlation of succinic acid and lactic acid concentration with the course of septic arthritis. Clinical Research 30(2): 659A, 1982

Serial gas liquid chromatographic analysis of synovial fluid correlation of succinic acid and lactic acid concentration with the course of septic arthritis. Arthritis & Rheumatism 25(4 SUPPL): S22, 1982

Ultrasound-guided synovial biopsy improves diagnosis of septic arthritis in acute arthritis without enough analyzable synovial fluid: a retrospective analysis of 176 arthritis from a French rheumatology department. Clinical Rheumatology 37(8): 2241-2249, 2018

Rapid diagnosis of septic arthritis by quantitative analysis of joint fluid lactic acid with a monotest lactate kit. Journal of Clinical Microbiology 8(6): 676-679, 1978

Synovial lactic acid and septic arthritis. JAMA 298(1): 40; Author Reply 40-40; Author Reply 40, 2007

Rapid diagnosis of septic arthritis by quantitative analysis of joint fluid lactic acid using the mono test lactate kit boehringer mannheim. Abstracts of the Annual Meeting of the American Society for Microbiology 78 : 292, 1978

Counterimmunoelectrophoresis of synovial fluid in the diagnosis of septic arthritis. Journal of Pediatric Orthopedics 5(2): 167-170, 1985

Synovial fluid lactate and the diagnosis of septic arthritis. Journal of Infection 6(3): 239-246, 1983

Role of synovial fluid lactate in the immediate diagnosis of septic arthritis. Clinical Research 28(4): 791A, 1980