EurekaMag.com logo
+ Site Statistics
References:
53,517,315
Abstracts:
29,339,501
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Syntheses of methoxy estrogen glucuronide acetate methyl esters



Syntheses of methoxy estrogen glucuronide acetate methyl esters



Chemical and Pharmaceutical Bulletin (Tokyo) 24(3): 421-426



In connection with studies on estrogen metabolism, methoxyestrogen glucuronide acetate-methyl esters having the 16,17-ketol and -glycol structures were prepared as new and potential metabolites. These compounds were satisfactorily obtained from catechol estrogen 2- and 3-methyl ethers by Koenigs-Knorr reaction with methyl acetobromoglucuronate employing cadmium carbonate as a catalyst.

(PDF 0-2 workdays service: $29.90)

Accession: 006559795

Download citation: RISBibTeXText

PMID: 1021248



Related references

Glucuronide conjugates of aldo sterone part 1 the preparation and properties of 2 isomeric 18 carbon tri o acetyl glucuronide methyl esters of aldo sterone 21 mono acetate. Steroids 20(4): 515-529, 1972

Aromatization of 1,6,7,7a-tetrahydro-2H-indol-2-ones by a novel process. Preparation of key-intermediate methyl 1-benzyl-5-methoxy-1H-indole-3-acetate and the syntheses of serotonin, melatonin, and bufotenin. Journal of Organic Chemistry 67(7): 2252-2256, 2002

Photochemical transformations of methoxy phthalaldehydic esters synthesis of methyl 6 methoxy phthalaldehyde from the 3 methoxy isomer. Journal of the Chemical Society Chemical Communications (18): 962-963, 1981

Metabolism of the anti-tumour drugs N2-methyl-9-hydroxyellipticinium acetate (NSC 264137) and N2-methyl-9-hydroxyolivacinium acetate in the rat: preliminary identification of biliary 9-(O)-glucuronide and 10-(S)-glutathione conjugates. Xenobiotica; the Fate of Foreign Compounds in Biological Systems 13(5): 303-310, 1983

Chemistry of 2 methoxy 2 5 cyclohexadienones 3. syntheses of 2 methoxy 4 4 diphenyl 2 5 cyclohexadienone and 4 dichloromethyl 2 methoxy 4 methyl 2 5 cyclohexadienone. Chemical and Pharmaceutical Bulletin (Tokyo) 32(12): 4721-4725, 1984

Syntheses of pyridazine derivatives. V. Syntheses of 3-methoxy-4-methyl-6-nitropyridazine 1-oxide. Yakugaku Zasshi 82: 1005-1012, 1962

Coclaurine and related compounds. II. Syntheses of 7-benzyloxy-1,2,3,4-tetrahydro-1-(p-hydroxyphenyl)-6-methoxy-2-methylisoquinoline and 7-benzyloxy-1,2,3,4-tetrahydro-1-(p-hydroxybenzyl)-6-methoxy-2-methyl-isoquinoline. (Studies on the syntheses of heterocyclic compounds. CLXXXV). Yakugaku Zasshi 87(7): 757-760, 1967

Syntheses of 1-(3-hydroxy-4-methoxphenethyl)-7-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline-6-ol and 1-(3-hydroxy-4-methoxybenzyl)-7-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline-6,8-diol and an attempt to cyclize the isoquinoline derivatives by phenol oxidation (Studies on the synthesis of heterocyclic compounds. 228. Yakugaku Zasshi 88(5): 583-588, 1968

Metabolism of the anti tumor drugs n 2 methyl 9 hydroxy ellipticinium acetate nsc 264137 and n 2 methyl 9 hydroxy olivacinium acetate in the rat preliminary identification of biliary 9 o glucuronide and 10 s glutathione conjugates. Xenobiotica 13(5): 303-310, 1983

Advanced oxidation and reduction process chemistry of methyl tert-butyl ether (MTBE) reaction intermediates in aqueous solution: 2-methoxy-2-methyl-propanal, 2-methoxy-2-methyl-propanol, and 2-methoxy-2-methyl-propanoic acid. Chemosphere 77(10): 1352-1357, 2010

High-temperature measurements of the reactions of OH with small methyl esters: methyl formate, methyl acetate, methyl propanoate, and methyl butanoate. Journal of Physical Chemistry. A 116(50): 12229-12241, 2013

(Syntheses Of Bisbenzylisoquinoline Alkaloids. I. Synthesis Of Dl-3-Amino-3'-Methoxy-4,4'-Bis(2-Methyl-6,7-Dimethoxy-1,2,3,4-Tetrahydro1-Isoquinolylmethyl)diphenyl Ether. (Studies On The Syntheses Of Heterocyclic Compounds. Ci.). Yakugaku Zasshi 84: 532-537, 1964

Glucuronide conjugates of aldosterone. 1. The preparation and properties of two isomeric C-18 tri-O-acetyl glucuronide methyl esters of aldosterone 21-monoacetate (1). Steroids 20(4): 515-529, 1972

Synthesis of methyl esters of uronic acids 2. synthesis of 2 3 di o methyl esters 2 4 di o methyl esters 3 4 di o methyl esters and 2 3 4 tri o methyl esters of methyl methyl alpha d galacto pyranoside uronate. Khimiya Prirodnykh Soedinenii (3): 283-285, 1982

Syntheses of the urinary metabolites of 1-(4-methoxy-6-methyl-2-pyrimidinyl)-3-methyl-5-methoxypyrazole (mepirizole, DA-398). Zeitschrift für Haut- und Geschlechtskrankheiten 44(24): 1908-1914, 1969