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Synthesis and anti convulsant activity of alkyl esters of 5 substituted 2 sulfamoyl benzoic acids



Synthesis and anti convulsant activity of alkyl esters of 5 substituted 2 sulfamoyl benzoic acids



Khimiko-Farmatsevticheskii Zhurnal 14(2): 20-25



A series of compounds were synthesized and anticonvulsant activity was studied in mice after i.p. administration in a suspension with Tween 80. Pharmacological activity was related to the chemical nature of the substituent in the complex ester group; isopropyl derivatives were most active.

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