+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Synthesis of some naturally occurring 4 methoxy coumarins



Synthesis of some naturally occurring 4 methoxy coumarins



Indian Journal of Chemistry Section B Organic Chemistry Including Medicinal Chemistry 14(8): 589-591



7-Hydroxy-4-methoxy-5-methylcoumarin [Platymiscium praccox] (II), a naturally occurring 4-methoxycoumarin was synthesized by the partial methylation of 4,7-dihydroxy-5-methylcoumarin. It was also synthesized directly from the known 4,7-dihydroxy-5-methylcoumarin ketimide by refluxing with methanolic hydrochloric acid. The condensation of II with tetraacetyl glucosyl bromide followed by deacetylation gives the glucoside, identical with the natural sample. The product obtained by refluxing 4-hydroxy-7-methoxy-5-methylcoumarin with methanol and HCl is identical with siderin [Sideritis canariensis and S. romana], another naturally occurring 4-methoxy-coumarin.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 006571173

Download citation: RISBibTeXText


Related references

Iso coumarins 4. synthesis of 5 6 di methoxy iso coumarins 6 7 di methoxy iso coumarins 7 8 di methoxy iso coumarins 5 7 di methoxy iso coumarins 5 8 di methoxy 3 methyl iso coumarins and a new synthesis of racemic 6 methoxy mellein. Proceedings of the Indian Academy of Sciences Chemical Sciences 89(6): 525-532, 1980

Removal of 4 hydroxyl group in 4 hydroxy 3 methoxy coumarins synthesis of 3 methoxy angelicin and partial methyl ethers of 3 methoxy coumarins. Indian Journal of Chemistry Section B Organic Chemistry Including Medicinal Chemistry 16(7): 587-590, 1978

Naturally occurring coumarin derivatives 17. synthesis of naturally occurring 5 methyl coumarins and 5 methyl chromones. Chemische Berichte 112(7): 2394-2401, 1979

Synthetic Studies on Naturally Occurring Coumarins. Ii. Synthesis of 6,7-Dimethoxy- and 7,8-Dimethoxy-5-((E)-3-oxo-1-butenyl)coumarins. Chemical & Pharmaceutical Bulletin 40(10): 2614-2619, 1992

Synthesis of some naturally occurring coumarins. Indian journal of chemistry: 12 (1) 23-25, 1974

Synthetic studies on naturally occurring coumarins. II. Synthesis of 6,7-dimethoxy- and 7,8-dimethoxy-5-coumarins. Chemical and Pharmaceutical Bulletin 40(10): 2614-2619, 1992

Total synthesis of naturally occurring 5,6,7-and 5,7,8-trioxygenated coumarins. Tetrahedron 64(19): 4438-4443, 2008

Naturally occurring Benzofuran: isolation, structure elucidation and total synthesis of 5-(3-Hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)-3-benzofurancarbaldehyde, a novel adenosine A1 receptor ligand isolated from Salvia miltiorrhiza Bunge (Danshen). Tetrahedron letters 32(18): 2061-2064, 1991

Synthetic studies on naturally occurring coumarins: I. A convenient synthesis of 5,8-dimethoxy- and 7,8-dimethoxycoumarins. Chemical & Pharmaceutical Bulletin (Tokyo) 40(7): 1770-1772, 1992

Convenient Synthesis of Naturally Occurring Methoxy-and Hydroxy Phthalides. Synthetic Communications 20(17): 2641-2652, 1990

Iso coumarins part 11 synthesis of 6 8 di amino 7 methoxy 3 methyl iso coumarin and related iso coumarins. Indian Journal of Chemistry 12(1): 57-59, 1974

Synthetic studies on naturally occurring coumarins II Synthesis of 6,7-dimethoxy- and 7,8-dimethoxy-5- -3-oxo-1-butenylcoumarins. Chemical & Pharmaceutical Bulletin (Tokyo) 40(10): 2614-2619, 1992

Naturally occurring coumarins. Fortschritte Der Chemie Organischer Naturstoffe 9: 225-291, 1952

The naturally occurring coumarins. Fortschritte der Chemie Organischer Naturstoffe 83: 1-619, 2002

The 13C-NMR spectrum of some naturally occurring coumarins. Yao Xue Xue Bao 17(11): 835-840, 1982