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Systemic and coronary hemodynamic effects of the new hypotensive drug l 6150


, : Systemic and coronary hemodynamic effects of the new hypotensive drug l 6150. Journal of International Medical Research 4(6): 402-409

The acute systemic and coronary hemodynamic effects of a new hypotensive drug L 6150 (3-hydrazino-6-[N,N-bis(2-hydroxyethyl)amino]pyridazine) were studied in 6 patients with renal or essential hypertension. The drug, administered i.v. at a dose of 2-9 mg, caused a marked hypotension and increase of cardiac output in 5 cases. Though left ventricular work was reduced or unchanged after the drug, myocardial blood flow increased markedly, coronary resistance decreased and coronary A-V [atrioventricular] O2 difference decreased by about 50% indicating coronary vasodilation. When compared with the available data on the effects of hydrazinophthalazine, L 6150 appeared to have qualitatively similar effects, but a somewhat greater direct coronary vasodilator effect.

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Figueiredo,M.V.B.; Burity,H.A.; Martinez,C.R.; Chanway,C.P., 2008: Alleviation of drought stress in the common bean by co-inoculation with Paenibacillus polymyxa and Rhizobium tropici. A greenhouse experiment was performed to evaluate the influence of <i>Rhizobium</i> when co-inoculated with each of two <i>Paenibacillus polymyxa</i> strains, singly and in mixture on growth, nitrogen content, phytohormone...

Diaz Mitoma, Francisco; Ruben, Martha; Sacks, Stephen; Macpherson, Paul; Caissiie, Gilberte, 1996: Detection of viral DNA to evaluate outcome of antiviral treatment of patients with recurrent genital herpes. Culture of infectious virus, PCR amplification of viral DNA, and the appearance of genital skin lesions were used as markers to study the course of a recurrence of genital herpes in 40 patients treated with famciclovir or placebo. The highest freq...

Kordas, Katarzyna; Lopez, Patricia; Rosado, Jorge L.; Ronquillo, Dolores; Alatorre, Javier; Stoltzfus, Rebecca J., 2003: Effects of iron and zinc supplementation on cognitive function of lead-exposed Mexican children. Lead is associated with poor nutritional status and cognitive performance. Iron competes with lead for absorption and zinc reverses inhibitory actions of lead. We conducted a 2x2 factorial, placebo-controlled trial of iron and zinc supplementation...

Hu, Howard; Sparrow, David; Weiss, Scott, 1992: Association of serum albumin with blood pressure in the normative aging study. Little is known regarding serum albumin's epidemiologic relation to chronic disease. The relation of serum albumin to blood pressure was assessed in a longitudinal study of men who have been seen at 3- to 5-year intervals since the early 1960...

Svadzhyan, E. P., 1963: Clinical experience with new analeptics; bemegride and ahypnon. New analeptics bemegride (Megimid) and ahypnon [long dash] antidotes of barbiturates were used in 102 cases. Analeptics are valuable agents, that stop or decrease barbiturate anesthesia, particularly in overdosage. They are recommended for treatme...

Engler M.J.; Dechavigny A.; Abbott F.J., 1986: Isolation of dna synthesis mutants of yeast. Journal of Cellular Biochemistry Supplement (10 PART B): 152

Egorenkova A.N., 1969: Variability of yeast like candida fungi with respect to the effect of the sodium salt of levorin anti infect. Antibiotiki (Moscow) 14(5): 430-432

Alfred S. Casale; Steven F. Bolling; Jing-An Rui; John T. Flaherty; Bernadine H. Bulkley; William E. Jacobus; Timothy J. Gardner, 1984: Progression and resolution of myocardial reflow injury. Journal of Surgical Research 37(2): 0-99

Norman M. Schechter, 1973: Studies of rna polymerase in mature avian erythrocytes. Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis 308(1): 0-136