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The cholinergic influence on the oxytocin activity of the hypothalamus and neuro hypophysis in long term dehydrated male rats


Acta Physiologica Polonica 29(1): 17-26
The cholinergic influence on the oxytocin activity of the hypothalamus and neuro hypophysis in long term dehydrated male rats
Rats dehydrated up to 12 days were injected i.p. with carbachol or atropine sulfate in daily doses of 20 .mu.g/100 g and 1.0 mg/100 g, respectively. In non-dehydrated rats atropine increased the oxytocin activity of the hypothalamus and neurohypophysis; carbachol did not influence the oxytocin potency of the hypothalamus but augmented it in the neurohypophysis. During long-term dehydration both carbachol and atropine intensified the depletion of oxytocin in the hypothalamus as well as in the neurohypophysis.


Accession: 006614514

PMID: 665246



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