The current state of research in the field of creating enzymes of microbial origin for medicinal purposes

Selezneva, A.A.; Grekova, V.K.; Moskvichev, B.V.; Kashkin, A.P.; Momot, N.N.; Tereshin, I.M.

Khimiko Farmatsevticheskii Zhurnal 11(10): 27-36


Accession: 006622947

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The basic directions in the creation and perfection of microbial enzymes for medicinal purposes in the USSR and abroad are reviewed. The accomplishments of theoretical and applied technology in the biosynthesis, isolation and chemical purification of enzymes, stabilization and study of immunogenic properties of microbial enzymes are discussed. Microbial sources cited include Escherichia coli, Penicillium sp., Aspergillus terricola, A. niger, Geotrichum asteroides, Curvularia inaequalis, Rhizopus, Streptomyces rimosus, S. fradiae, Thermoactinomyces vulgaris, Bacillus mesentericus, B. subtilis, P. chrysogenum, A. oryzae, A. flavus and S. griseus.