+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The dexamethasone suppression test: interaction of diagnosis, sex, and age in psychiatric inpatients

Biological Psychiatry 19(9): 1293-1304

The dexamethasone suppression test: interaction of diagnosis, sex, and age in psychiatric inpatients

A group of 277 semiconsecutive psychiatric inpatients manifesting a depressive affect underwent an overnight 1 mg dexamethasone suppression test (DST) and a semistructured diagnostic interview according to DSM-III [Diagnostic and Statistical Manual of Mental Disorders, III], criteria. For major depressive syndromes (major depression with and without psychosis, bipolar depressed) the sensitivity of the DST was 63.9%, specificity 73.0% and diagnostic confidence 72.3%. Additionally, a significant interaction between age and baseline cortisol values and nonsuppression rates was found in depressed males but not in nondepressed males nor in depressed and nondepressed females. Implications of these findings are discussed.

Accession: 006628152

PMID: 6498252

Related references

Hwu H G.; Lin H N., 1990: Serial dexamethasone suppression test in psychiatric inpatients. A sample of 100 consecutively admitted cases were recruited to test the hypothesis that an abnormal dexamethasone suppression test (AbDST) is associated with decreasing clinical severity during the course of hospitalization in various diagnostic c...

Targum, S.D.; Capodanno, A.E., 1983: The dexamethasone suppression test in adolescent psychiatric inpatients. The dexamethasone suppression test (DST) was administered to 120 adolescent psychiatric patients at the time of hospitalization, and cortisol levels were measured at 4:00 p.m. and 11:30 p.m. on the day after a 1-mg oral dose of dexamethasone was g...

Jeong D U.; Woo J.I., 1986: The dexamethasone suppression test findings in psychiatric inpatients. 83 Subjects (20 normal controls, 15 neurotics, 19 major depressives and 29 paranoid schizophrenics) underwent the dexamethasone suppression test (DST) to test the applicability of the test for the diagnosis of major depression. Pre- and post-dexam...

Kerr-CorrĂȘa, F.; Carlini, E.A.; Sonenreich, C., 1990: The dexamethasone suppression test applied to inpatients of a Brazilian psychiatric hospital. 1. The Dexamethasone Suppression Test (DST) was applied to three groups of Brazilian psychiatric inpatients as follows: 93 patients were tested both on admission and at discharge; 166 patients were tested only on admission, and 43 patients only at...

Steiner M.; Brown G.M., 1984: Melatonin cortisol ratio and the dexamethasone suppression test in newly admitted psychiatric inpatients. Journal of Steroid Biochemistry 20(6 PART B): 1468

Zimmerman, M.; Coryell, W.; Corenthal, C., 1984: Attribution style, the dexamethasone suppression test, and the diagnosis of melancholia in depressed inpatients. Journal of Abnormal Psychology 93(4): 373-377

Jeong D U.; Woo J.I.; Lee C.K., 1983: Utilization of dexamethasone suppression test in psychiatric diagnosis. Subjects (39), 20 normal controls and 19 major depressive patients) underwent a DST [dexamethasone suppression test] to prove the applicability of the test for the diagnosis of major depressive disorder (DSM-III [Diagnostic and Statistical Manual...

Pollock, D.C.; Sheehan, M.E., 1982: Objectifying psychiatric diagnosis and treatment with the dexamethasone suppression test. The application of the dexamethasone suppression test (DST) to the treatment of depressive illness is discussed from the perspectives of its use in diagnosis, the measurement of outcome, and the prediction of response to antidepressant medications...

Dichek, H.L.; Nieman, L.K.; Oldfield, E.H.; Pass, H.I.; Malley, J.D.; Cutler, G.B., 1994: A comparison of the standard high dose dexamethasone suppression test and the overnight 8-mg dexamethasone suppression test for the differential diagnosis of adrenocorticotropin-dependent Cushing's syndrome. To improve the overnight 8-mg dexamethasone (DEX) suppression test (DST) for differential diagnosis of Cushing's syndrome and to develop optimal criteria for its interpretation, we increased the number of blood samples and measured the suppre...

Hwu, H.G.; Lin, H.N.; Lu, R.B., 1987: Dexamethasone suppression test in psychiatric diagnosis and psychopathology for Chinese patients. The rate of abnormal dexamethasone suppression test (AbDST, post-dexamethasone cortisol greater than 5.0 micrograms/dl) was analyzed in different psychiatric samples, diagnostic categories and different time points of blood sampling. Differences i...