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The diagnosis of aspirin idiosyncrasy by analgesic challenge

, : The diagnosis of aspirin idiosyncrasy by analgesic challenge. Clinical Allergy 6(2): 177-181

Analgesic challenge was employed to identify fifty patients with aspirin idiosyncrasy. No serious reactions were observed using the method described. Patients with a history of the condition were highly sensitive and reacted to small doses of aspirin or to paracetamol. Patients with a positive challenge test, but previously unaware of aspirin idiosyncrasy, were less sensitive; they required larger challenge doses of aspirin and did not respond to paracetamol challenge. In the absence of an in vitro test, analgesic challenge is the only means of confirming the presence of aspirin idiosyncrasy.

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Accession: 006628304

PMID: 1277441

DOI: 10.1111/j.1365-2222.1976.tb01896.x

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Boesgaard S.; Poulsen H.E.; Aldershvile J.; Loft S.; Anderson M.E.; Meister A., 1992: Hemodynamic effect of nitroglycerin is affected by high extracellular and low intracellular sulfhydryl levels in vivo. European Heart Journal 13(ABSTR SUPPL): 166

Liu, M.H.; He, G.W., 2000: Inhibition of vasoconstriction by AJ-2615, a novel calcium antagonist with alpha1-adrenergic blocking activity in human conduit arteries used as bypass grafts. FASEB Journal 14(4): A166, March 15

Clough, J., 2003: A new era as plate movers get on track. Drug Discovery Today 7(16): 856-857

Davis, H., 1964: Enhancement Of Evoked Cortical Potentials In Humans Related To A Task Requiring A Decision. The averaged, slow response evoked by auditory stimuli and recorded from the vertex of the human skull can usually be enhanced by requiring the listener to make a rather difficult auditory discrimination. An easy routine reaction is not effective.

Dancewicz, R.; Barcikowski, S.; Zielinski, K.W.; Kulig, A.; Sygut, J., 1988: Investigations on lung traumas by blast in rabbits 2. the pathogenetic mechanism of the lung trauma hypothesis. A hypothesis of the pathogenetic mechanism of the pulmonary changes after the injury is introduced. Basis are the results of the morphologic estimation of the lung traumas by blast with known energy in rabbits. The reason is the lung deformation b...

Roberts, M., 1993: European pulp and paper makers decide on process change. Chemical week, 152(15): 34-35

Il'in, V.S.; Bistritskaite, D., 1967: Activity of glucose-C-phos-phatase in the liver and kidney of hypophysectomized rats and the induction of its synthesis after an adrenocorticotropic hormone and hydro -cortisone injection. Extirpation of the hypophysis provokes a considerable decrease in glucose-6-phosphatase (G-6-P) activity in rat liver and kidney. Intramuscular administration of ACTH (for 4 days) does not provoke any essential alteration in the G-6-P activity in...

Chesunov, A.V., 1978: New free-living nematodes from the order Araeolaimida from the Caspian sea. Three marine nematodes found in the southern Caspian Sea, USSR, are described. Campylaimus tkatchevi n.sp. differs from C. gerlachi in the dorsal position of the mouth, in the short cephalic setae and the position of the excretory pore (behind the...

Bourgault, P.; Karczmar, A.G., 1961: Behavioral and pharmacological differences among certain strains of mice. FED PROC 20(1 Pt 1): 321

Segal, I.; Walker, A.R.; Naik, I.; Riedel, L.; Daya, B.; de Beer, M., 1991: Malabsorption of carbohydrate foods by urban blacks. Prevalences of non-infective bowel diseases are very low in South African urban blacks compared with the white population. In seeking elucidation, using breath hydrogen measurements in series of black and white subjects, small-bowel transit time w...