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The diagnosis of stuart prower disease


, : The diagnosis of stuart prower disease. Problemy Gematologii i Perelivaniya Krovi 22(3): 46-49

Two brothers showed clinical symptoms indicating either coagulation disorders or hemophilia, including late bleeding after tooth extraction and surgery. These hemorrhages were successfully treated with preserved plasma transfusions, suggesting a factor .times. deficiency. Frequent nosebleeds also seemed to indicate such a diagnosis. Coagulographic analyses confirmed this suspicion. An analogous but unmanifested disorder was present in the boys' father, while the mother and other relatives showed no such disturbance. Analysis of the condition of blood coagulation as a whole and of its phases is sufficient for the diagnosis of isolated coagulation defects, and special tests of the activity of each factor are unnecessary.


Accession: 006628475

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Related references

Papaian, L.P.; Fedorova, Z.D.; Medved', R.I.; Khrolova, P.V., 1977: Diagnosis of Stuart-Prower disease. Problemy Gematologii i Perelivaniia Krovi 22(3): 46-49

Tullis, J.L.; Melin, M., 1968: Management of Christmas disease and Stuart-Prower deficiency with a prothrombin-complex concentrate (factors II, VII, IX, X). Bibliotheca Haematologica 29: 1134-1139

André, R.; Duhamel, G.; Vergoz, D.; Rochant, H., 1966: Hemorrhagic syndrome caused by acquired Stuart-Prower factor deficiency. Amyloidosis. Waldenstrom's disease. Bulletins et Memoires de la Societe Medicale des Hopitaux de Paris 117(1): 41-48

Anonymous, 1959: Hemorrhagic syndrome rapidly curable by vitamin K during insufficiently treated celiac disease Role of the Prower-Stuart factor

Roos, J.; Va.A.Kel, C.; Verloop, M.C.; Jordan, F.L., 1959: A new family with Stuart-Prower deficiency. Thrombosis et Diathesis Haemorrhagica 3(1): 59-76

Duckert, F., 1960: On the properties of the Stuart-Prower factor. Thrombosis et Diathesis Haemorrhagica 4(Suppl): 32-36

Schulz, J.; Va.C.Eveld, S., 1958: Stuart-Prower factor in newborn infants. Etudes Neo-Natales. Neo-Natal Studies 7(4): 133-142

Quast, U.R.; Sibinga, C.T.; Wijnja, L., 1971: Stuart-Prower factor deficiency and oral surgery. British Journal of Oral Surgery 9(21): 146-150

Anonymous, 1960: Prower-Stuart clotting defect Some characteristics of the factor

Dorantes, S.; Soto, R.; Castrejon, O., 1960: "Prower-Stuart" coagulation defect. Various characteristics of the factor. Boletin Medico del Hospital Infantil de Mexico 17: 139-156