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The diagnostic and therapeutical problems of latent toxoplasmosis in pregnancy

The diagnostic and therapeutical problems of latent toxoplasmosis in pregnancy

Wiadomosci Parazytologiczne 30(3): 321-330

In the 1st Obstetric Clinic at the Medical Academy in Wroclaw [Czechoslovakia] 614 pregnant women, who have been hospitalized with various clinical diagnoses during 8 yr (1974-1981), had a positive serologic test which indicated toxoplasmosis. Although in 75% of cases no therapy was undertaken, toxoplasmosis was not diagnosed in either mothers or infants. As the currently serologic tests are often unreliable an attempt should be made to establish more precise laboratory critera qualifying for treatment of toxoplasmosis in pregnancy. Although the opinions on the efficacy of asymptomatic toxoplasmosis therapy in pregnancy are divided, no complications (in mother or in fetus) result from such treatment, while nontreatment may have its moral and legal consequences. Antitoxoplasma therapy seems necessary for every woman with positive serologic result and obsterical anamnesis, especially in those cases where the change of titer from negative to positive or an ascending titer have been observed.

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