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The effect of serotonin application to the dorsal hippocampus on conditioned passive and active avoidance reflexes in rats



The effect of serotonin application to the dorsal hippocampus on conditioned passive and active avoidance reflexes in rats



Byulleten' Eksperimental'noi Biologii i Meditsiny 101(5): 517-519



It has been established that intrahippocampal bilateral injection of 5-HT in a dose of 2 .mu.g prolonged the time of passive avoidance reflex retention, inhibiting the retrieval of active avoidance reflex and facilitating its extinction. The data obtained show the dependence of 5-HT effect on reinforcing and triggering properties of spatial-environmental and phasic conditioned stimuli. It is suggested that intrahippocampal 5-HT administration was responsible for the retrieval of traces of conditioned reinforced stimuli.

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Accession: 006653965

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