EurekaMag.com logo
+ Site Statistics
References:
47,893,527
Abstracts:
28,296,643
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The electrogenic sodium dependent iodide transport system in plasma membrane vesicles from thyroid glands


, : The electrogenic sodium dependent iodide transport system in plasma membrane vesicles from thyroid glands. Biochimica et Biophysica Acta 896(2): 263-274

Using vesicles from the plasma membrane of hog thyroid, we have characterized its Na+-dependent I- transport system. We have found it to be totally Na+ dependent: K+ cannot substitute and Li+ can partially substitute for Na+; the Na+:I- flux ratio is larger than one; the system is electrogenic, being stimulated by a .DELTA.psi. negative inside the vesicles. A number of large, lipophilic anions are fully-competitive inhibitors of Na+-dependent I- uptake; the closer their atomic radii are to that of iodine, the smaller their Ki values.


Accession: 006670393

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

O'Neill, B.; Magnolato, D.; Semenza, G., 1987: The electrogenic, Na+-dependent I- transport system in plasma membrane vesicles from thyroid glands. Using vesicles from the plasma membrane of hog thyroid, we have characterized its Na+-dependent I- transport system. We have found it to be totally Na+ dependent; K+ cannot substitute and Li+ can partially substitute for Na+; the Na+:I- flux ratio...

Saito, K.; Yamamoto, K.; Takai, T.; Yoshida, S., 1982: The sodium-dependent iodide transport by phospholipid vesicles reconstituted with the thyroid plasma membrane. The I- transport system in the thyroid plasma membrane (PM) was successfully reconstituted in phospholipid vesicles (P-vesicles) by sonication. P-vesicles thus prepared were able to concentrate I- in the presence of external Na+. The activity of t...

Saito K.; Yammoto K.; Takai T.; Yoshida S., 1982: The sodium dependent iodide transport by phospho lipid vesicles reconstituted with thyroid plasma membrane. The I- transport system in the [rat] thyroid plasma membrane (PM) was successfully reconstituted in phospholipid vesicles (P-vesicles) by sonication. P-vesicles thus prepared were able to concentrate I- in the presence of external Na+. The activit...

Saito, K.; Yamamoto, K.; Nagayama, I.; Uemura, J.; Kuzuya, T., 1989: Effect of internally loaded iodide, thiocyanate, and perchlorate on sodium-dependent iodide uptake by phospholipid vesicles reconstituted with thyroid plasma membranes: iodide counterflow mediated by the iodide transport carrier. Na+-dependent I- transport and I- counterflow were studied using phospholipid vesicles (P-vesicles) made of porcine thyroid plasma membranes and soybean phospholipid by sonication. 1) I- uptake by P-vesicles incubated in the presence of external N...

Saito K.; Yamamoto K.; Nagayama I.; Uemura J.; Kuzuya T., 1989: Effect of internally loaded iodide thiocyanate and perchlorate on sodium dependent iodide uptake by phospholipid vesicles reconstituted with thyroid plasma membranes iodide counterflow mediated by the iodide transport carrier. Na+-dependent I- transport and I- counterflow were studied using phospholipid vesicles (P-vesicles) made of porcine thyroid plasma membranes and soybean phospholipid by sonication. 1) I- uptake by P-vesicles incubated in the presence of external N...

Stremmel W., 1986: Evidence of electrogenic sodium dependent fatty acid transport in basolateral rat liver plasma membrane vesicles. Journal Of Hepatologypl. 1: S67

O'neill B.; Isely A.; Magnolato D.; Semenza G., 1987: Sodium dependent iodine transport in thyroid plasma membrane vesicles. Alvarado, F And C H Van Os (Ed ) Inserm (Institut National De La Sante Et De La Recherche Medicale) Symposium, No 26 Ion Gradient-Coupled Transport; International Symposium on 25 Years Of Research on The Brush Border Membrane And Sodium-Coupled Transport, Aussois, France, September 18-20, 1985 Xxvii+442p Elsevier Science Publishers: Amsterdam, Netherlands (Dist in The Usa And Canada By Elsevier Science Publishing Co , Inc : New York, New York, Usa) Illus 309-312, 1986

Saito, K.; Yamamoto, K.; Nagayama, I.; Uemura, J.; Kuzuya, T., 1989: Preservation of sodium-dependent iodide transport activity by methimazole and mercaptoethanol in phospholipid vesicles containing thyroid plasma membranes: with evidence of difference in the action of perchlorate and thiocyanate. The effect of methimazole (MMI) and 2-mercaptoethanol (ME) on I-transport was studied using phospholipid vesicles (P-vesicles) made from porcine thyroid plasma membranes and soybean phospholipids by sonication. 1. When buffer solutions contained e...

Gerencser, G.A., 1988: Electrogenic ATP-dependent Cl- transport by plasma membrane vesicles from Aplysia intestine. A Cl--stimulated adenosinetriphosphatase (ATPase) activity and an ATP-dependent Cl- transport process were found in Aplysia enterocyte plasma membranes. In an attempt to further elucidate this transport process plasma membrane vesicles from Aplysi...

Golstein P.; Beauwens R., 1990: Iodide transport across plasma membrane vesicles from bovine thyroid. Archives Internationales de Physiologie et de Biochimie 98(1): P29-P30