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The electrophysiological and morphological analysis of the cardiotoxic effect of ethanol in rats


Farmakologiya i Toksikologiya (Moscow) 49(3): 110-114
The electrophysiological and morphological analysis of the cardiotoxic effect of ethanol in rats
The experiments on male rats showed that oral ethanol administered in a dose of 8 g/kg (2/3 of LD50) daily for a month produces toxic heart damage whose electrophysiological and morphological characteristics are similar to clinicoanatomical manifestations of human alcohol myocardiodystrophy. It was concluded that the model may be used for the search of new pharmacological agents for the treatment and prevention of alcohol myocardiodystrophy.


Accession: 006670537



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