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The elimination of drugs into saliva


, : The elimination of drugs into saliva. Farmaceuticky Obzor 53(1): 27-31

The elimination of drugs into saliva has been extensively studied during the past years. Some modes of elimination of drugs into saliva are given. The advantage and disadvantage of determination of drug level in saliva against plasma and the examples of theoretical monitoring by the determination of drug level in saliva are also discussed. The problem of elimination of drugs into saliva is concentrated for the time being on a few drugs and therefore it is impossible now to draw final conclusions concerning other drugs.


Accession: 006670644

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Related references

Farmer, T.W.; DeAngelis, R.L.; Welch, R.M., 1975: Effect of anticonvulsant drugs on the drug metabolism in man as measured by the elimination rate of antipyrine from saliva. Transactions of the American Neurological Association 100: 190-191

Li, P-wang.; Wang, Y-jin.; Liu, J-fang., 2007: Analysis on the abused drugs in saliva and correlation of saliva drugs concentrations with blood concentrations. Saliva is an easily collected body fluid and has simple composition. Some drugs concentrations in saliva can reflect their blood level. This paper analyzes the mechanisms of drug transfer from blood into saliva and the influencing factors, reviews...

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