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The emergence of sv 40 variants in a persistent infection of rhesus monkey kidney cells and their interaction with standard sv 40


, : The emergence of sv 40 variants in a persistent infection of rhesus monkey kidney cells and their interaction with standard sv 40. Virology 95(2): 598-614

In a persistent infection of rhesus monkey kidney cells with SV40, a heterogeneous population of variant particles emerges to replace the large plaque standard SV40 used to initiate the infection. The variants include defective interfering (DI) particles which reach detectable levels at week 6 and which are in excess of plaque forming units (PFU) by week 9. Stocks which contain an excess of DI particle activity contain an excess of particles able to produce T antigen, but not V antigen. Homotypic interference by SV40 DI particles results from a competitive interaction with standard SV40 during replication. Between 7-10 wk of persistent infection, the large-plaque standard SV40 is replaced by infectious small-plaque particles. Between 14-28 wk, the uncloned carrier culture stocks became temperature-sensitive for replication. Restriction endonuclease analysis revealed some changes in carrier culture viral DNA with the first changes evident by week 2. As late as week 57, most of the viral DNA from the carrier system yielded restriction endonuclease fragments indistinguishable from standard virus fragments.

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Borchert H., 1969: The known ore deposits and geochemistry of manganese. Different kinds of deposits, distribution, genesis.

Bermudez, I.; Orellana, P. P.; Perez Ponce, J. P.; Clavero, J.; Veitia, N.; Romero, C.; Mujica, R.; Garcia, L. R., 2000: Improvement of the hybrid plantain clone FHIA-21 by mutagenesis in vitro. The objective of this work was the production of gamma -induced mutants with short stature and Mycosphaerella fijiensis resistance. Tissue cultured plantlets were gamma -irradiated at 25 Gy and information on yield components and M. fijiensis r...

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Okamura, Shoji; Naito, Keiko; Sonehara, Kazuhiko; Ohkawa, Hiromi; Kuramori, Shioko; Tatsuta, Maki; Minamizono, Mikado; Kataoka, Tomoaki, 1997: Characterization of the carrot beta-tubulin gene coding a divergent isotype, beta-2. Four different beta-tubulin clones were isolated from carrot genomic and cDNA libraries. Their nucleotide sequences were determined and their predicted amino acids were compared with each other. The predicted amino acid composition of the C-termin...

Oie, Gunvor; Makridis, Pavlos; Reitan, Kjell Inge; Olsen, Yngvar, 1997: Protein and carbon utilization of rotifers in first feeding of turbot larvae. The effect of three different rotifer enrichments was examined on growth, survival, pigmentation and viability of first feeding turbot larvae. The diets differed in rotifer content of protein, lipid and ratio of protein/lipid. The diets were fed t...

Ellsworth, Ethan.; Belthoff, James R., 1997: Sex-biased dispersal of young western screech-owls (Otus kennicottii) in southwestern Idaho. U S Forest Service General Technical Report NC: 190: 155-159

Bouillard, C.; Miegeville, M.; Vermeil, C., 1982: Studies in vivo and in vitro of the interrelations between Schistosoma mansoni and some enterobacteria. Mice with 20-day-old S. mansoni infection were infected by mouth with bacterial cultures. Salmonella typhimurium colonies were recovered in cultures of adult male schistosomes but not from schistosomula. Very few females were colonized by bacteria...

Chaudhary, S. L.; Mahato, N., 1989: Section 1. Contributed papers involving several NFT genera. Nepal. One short paper: Effect of different sources of green manure on yield of improved rice. Data are reported on relative increases in rice grain yield promoted by green manuring with Sesbania aculeata, S. rostrata, Phaseolus aureus [Vigna radiata] an...

Stelzleni, A. M.; Johnson, D. D., 2008: Effect of days on concentrate feed on sensory off-flavor score, off-flavor descriptor and fatty acid profiles for selected muscles from cull beef cows. The effects of short-term realimentation (0, 42 or 84 days) of cull beef cows (n = 24) and post-mortem aging (10 or 20 days) of selected muscles on sensory off-flavor score, off-flavor descriptors of m. Gluteus medius (GLM), m. Longissimus lumbor...

Murray J.A., 1969: Cardiac factors influencing general anesthesia for oral surgery. Journal of Oral Surgery 27(8): 633-636