EurekaMag
+ Translate
+ Most Popular
Allopurinol and Loss of Consciousness in a 78-old Year Man Suffering from Gout
The parasites of British birds and mammals. 3XIV-3XVH
Studies on the in vitro synthesis of phi x 174 super helical covalently closed circular duplex dna and circular single stranded dna
The Shahada movement: a peasant movement in Maharashtra (India) - its development and its perspectives
The cranial nerves of Wallago attu
Anatomy of Mystus seenghala IV Nervous system
Haematology of Persian fallow deer (Dama mesopotamica)
Major weeds of rabi and kharif crops and their control
Structure of Morija-Banol iron-ore deposits, Rajasthan, and its control over mineralization
Donkioporia expansa - A lesser known wood destroyer in buildings
The new physiology of vision 3Xin. The testing of color-vision
Economic importance of Pteridophytes
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
Ketoconazole shampoo 1% vs. climbazole shampoo in the treatment of seborrhoeic scalp dermatitis
Economic efficiency of biwall drip irrigation in sugarcane production - a case study in Ankalkhop village in Sangli District of Maharashtra
48,4X-49,5X mosaic: asynchronies among the late-replicating X chromosomes
Compatibility of potassium phosphonate (Akomin-40) with different species of Trichoderma and Gliocladium virens
Enterobacter amnigenus. An unusual human pathogen
The 48 4X 49 4Xy 49 4X iso chromosome yq mosaicism in a 3 year old boy from a twin pregnancy
Placentrex treatment in corneal defects in animals
The biology of human starvation: some new insights
Real-time PCR assays for the specific detection of monkeypox virus West African and Congo Basin strain DNA
Replenishable but depletable resources: water
New insights into bestiality and zoophilia
Thoracic outlet syndrome in Ehlers-Danlos patients as displayed by magnetic resonance imaging, angiography and venography

The flow of substrate molecules in fast enzyme catalyzed reaction systems


The flow of substrate molecules in fast enzyme catalyzed reaction systems



Chemica Scripta 16(5): 192-196



ISSN/ISBN: 0004-2056

For enzyme-substrate fast reaction systems with cavity active site, the flow-line charts are calculated to investigate how the substrate molecules, governed by the diffusive and molecular forces, move to the active site. These flow-line charts show that the van der Waals' short-range force exerts a considerable influence on the orbits of the bimolecular reactions. As a result, the flow lines are particularly dense in a very thin shell along the enzyme surface. This means that a majority of the substrate molecules get to the active site through such a way, and also reflects the role played by the enzymatic protein outside the active site during catalysis. The mathematical model of the cavity active site, the flow-line equation and its calculation method are presented.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 006678536

Download citation: RISBibTeXText

Related references

A semi-analytical expression for the concentration distribution of substrate molecules in fast, enzyme-catalysed reaction systems. Biochimica et Biophysica Acta 657(1): 304-308, 1981

A semi-analytical expression for the concentration distribution of substrate molecules in fast, enzyme-catalysed reaction systems. Biochimica et Biophysica Acta (Bba) - Enzymology 657(1): 304-308, 1981

On the substrate specificity of the flavine enzyme hydroxynitrile lyase d oxynitrilase and on the reaction mechanism of the reaction catalyzed by the enzyme. Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie 353(5): 698-699, 1972

Substrate specifity of the flavin enzyme hydroxynitrile lyase (D-oxynitrilase) and mechanism of the reaction catalyzed by the enzyme. Hoppe-Seyler's Zeitschrift für Physiologische Chemie 353(5): 698-699, 1972

Influence of slow substrate conversion on an enzyme reaction ii. multiple steady state model for the reaction catalyzed by glyceraldehydephosphate dehydrogenase. Molekulyarnaya Biologiya 19(5): 1273-1277, 1985

Influence of slow substrate conversions on an enzyme reaction i. role of pyruvate forms in the steady state reaction catalyzed by lactate dehydrogenase. Molekulyarnaya Biologiya 19(4): 1092-1099, 1985

The Enzyme-Substrate Complex in a Muramidase (Lysozyme) Catalyzed Reaction. Journal of Biochemistry 55: 516-521, 1964

Studies on cell enzyme systems. II. Evidence for enzyme-substrate complex formation in the reaction of Cypridina luciferin and luciferase. Arch Biochem 23(3): 385-393, 1949

Studies on cell enzyme systems; evidence for enzyme-substrate complex formation in the reaction of Cypridina luciferin and luciferase. Archives of Biochemistry 23(3): 385-393, 1949

The quantitative relations between diffusion-controlled reaction rate and characteristic parameters in enzyme-substrate reaction systems. I. Neutral substrates. Scientia Sinica 19(1): 117-136, 1976

QM/MM Study of the Reaction Catalyzed by Alkyladenine DNA Glycosylase: Examination of the Substrate Specificity of a DNA Repair Enzyme. Journal of Physical Chemistry. B 121(49): 11096-11108, 2017

Enzyme catalyzed biotransformations in aqueous two-phase systems with precipitated substrate and/or product. Biotechnology and Bioengineering 45(3): 261-267, 1995

The quantitative relations between diffusion controlled reaction rate and characteristic parameters in enzyme substrate reaction systems part 2 charged substrates. Scientia Sinica 18(3): 366-380, 1975

The role of amyloses of different chain length as donor molecules and acceptor molecules in the transferase reaction of potato d starch branching enzyme q enzyme. Federation Proceedings 31(2): 477, 1972

RNA size is a critical factor for U-containing substrate selectivity and permanent pseudouridylated product release during the RNA:Ψ-synthase reaction catalyzed by box H/ACA sRNP enzyme at high temperature. Biochimie 113: 134-142, 2015