+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The ideal human neoplasm

, : The ideal human neoplasm. Medical Hypotheses 5(10): 1133-1140

Clinical cancer manifestations are divided into the following 3 categories: primary cancer manifestations, e.g., cachexia; neoplasia, generally regarded as a local phenomenon; and secondary systemic sequelae of neoplasia, e.g., functional loss due to metastatic involvement. The theory coined as the Ideal Human Neoplasm (IHN) outlines the salient features of neoplastic progression and provides a framework in which this change may be expressed precisely and rigorously. Neoplasia is manifested by the follow 3 elementary biological phenomena: proliferation, differentiation and morphologenesis. Neoplasma are classified according to their replicative tissue group origin into 2 major groups: type I, which rise from rapidly replicating organs such as bone marrow, gastro-intestinal mucosa and endometrium; and type II neoplasma, originating in slowly proliferating organs, e.g., liver and kidney. The theory deals solely with adult type I neoplasms. It provides laws common to all type I neoplasms and outlines a common developmental pathway shared by all of them. Neoplasia is regarded as organ manifestation, a notion which disagrees with the commonly accepted one which regards neoplasia solely as a tissue manifestation. for is For instance, colon carcinoma viewed as an aberration of the whole mucosa and not only of its epithelial tissue. Carcinogenesis is marked by 2 processes proceeding together. A gradual and continuous expansion of progenitor cells is accompanied by their dedifferentiation. IHN forms a part of a more generalized theory which views neoplasia as a protective mechanism mobilized by the organism to withstand the gradual systemic deterioration of cancer, e.g., cachexia.

Accession: 006689232

PMID: 522700

DOI: 10.1016/0306-9877(79)90031-8

Download PDF Full Text: The ideal human neoplasm

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Related references

Phillips, T., 2011: From the ideal market to the ideal clinic: constructing a normative standard of fairness for human subjects research. Preventing exploitation in human subjects research requires a benchmark of fairness against which to judge the distribution of the benefits and burdens of a trial. This paper proposes the ideal market and its fair market price as a criterion of fa...

Amaki I.; Takizawa Y.; Higo O.; Ueki Y.; Hagihara T., 1968: Serial observations of the fibrous tissue in the bone marrow of hematological disorders human blood neoplasm res neoplasm. Tohoku Journal of Experimental Medicine 96(4): 379-391

Merenda, P.F.; Mohan, J.; Shaw, B.J., 1975: Indian students' perceptions of the ideal self, the ideal leader, the ideal teacher, Indira Gandhi and the business executive. The Activity Vector Analysis (AVA) was administered to three samples drawn from a population of graduate students at an Indian university. Results indicated a high positive relationship among the perceptions of the ideal self, ideal teacher, and i...

Ferguson Robert B., 1982: The K-feldspar structural end-members ideal sanidine, ideal orthoclase and ideal maximum-microcline. Program with Abstracts - Geological Association of Canada(Mineralogical Association of Canada(Canadian Geophysical Union, Joint Annual Meeting 7: 49

van de Spijker, A.M., 1977: Masculinity--an ideal? Womanliness--an ideal? Pastoral-theological studies on current endocrinology. Die Medizinische Welt 28(4): 194-197

Mizuma, R., 2005: A study on the structure of the intention to become ideal selves: from the viewpoint of the relationship to subjective ratings of ideal selves. This study examined the structure of the "intention to become ideal selves", the autonomous direct approaches in building into an ideal self. Only when people feel meanings or worth on an ideal self, do people have the intention to be it...

Barzegarinegad, A.; Jahanshahloo, G.; Rostamy-Malkhalifeh, M., 2015: A full ranking for decision making units using ideal and anti-ideal points in DEA. We propose a procedure for ranking decision making units in data envelopment analysis, based on ideal and anti-ideal points in the production possibility set. Moreover, a model has been introduced to compute the performance of a decision making un...

Cox, D.J., 1971: Computer simulation of sedimentation in the ultracentrifuge. V. Ideal and non-ideal monomer-trimer systems. Archives of Biochemistry and Biophysics 142(2): 514-526

Merenda, P.F.; Clarke, W.V.; Schulz, H.; Strehse, W.; Winneke, G., 1970: Differences in perception of concept of ideal-self and ideal-person between American and German samples. Perceptual and Motor Skills 30(3): 783-786

Thierry Worch; Sébastien Lê; Pieter Punter; Jérôme Pagès, 2012: Construction of an Ideal Map IdMap based on the ideal profiles obtained directly from consumers. In this paper, the <italic>Ideal Mapping</italic> technique is presented. It is similar to the <italic>Preference Mapping</italic> technique using the quadratic model proposed by Danzart. Indeed, both methods start from the...