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The identification of the active sites in human ceruloplasmin from the computer analysis of intermolecular and intramolecular homology


, : The identification of the active sites in human ceruloplasmin from the computer analysis of intermolecular and intramolecular homology. Molekulyarnaya Biologiya (Moscow) 21(4): 1124-1129

The identification of possible copper ligands in human ceruloplasmin was carried out by the computer similarity analysis for sequences of ceruloplasmin and several other copper oxidases: azurin, plastocyanin, superoxide dismutase, tyrosinase and hemocyanin. It follows from the analysis of inter- and intramolecular homology that copper active sites of different types appeared to be in close contacts within the ceruloplasmin molecule.


Accession: 006689552

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Related references

Moshkov, K.A.; Vagin, A.A.; Zaĭtsev, V.N., 1987: Localization of active sites in human ceruloplasmin from data of intra- and intermolecular homology. The identification of possible copper ligands in human ceruloplasmin was carried out by the computer similarity analysis for sequences of ceruloplasmin and several other copper oxidases: azurin, plastocyanin, superoxide dismutase, tyrosinase and h...

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