EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The low 3rd molar and anti phlogistics effects of betamethasone ibuprofen indomethacin naproxen niflumic acid oxyphen butazone tranexamic acid and glafenine on the patients condition after surgical removal of a lower 3rd molar


, : The low 3rd molar and anti phlogistics effects of betamethasone ibuprofen indomethacin naproxen niflumic acid oxyphen butazone tranexamic acid and glafenine on the patients condition after surgical removal of a lower 3rd molar. International Journal of Oral Surgery 11(6): 340-350

A multidisciplinary, double-blind, parallel placebo controlled investigation was made to find an effective antiinflammatory drug which prevents postoperative swelling, trimus and a general feeling of malaise. The antiinflammatory properties of antirheumatics were also objectively evaluated. In 126 healthy patients, who were without complaints, the lower 3rd molar was surgically removed. A drug was taken orally according to a fixed scheme for 4 days. Glafenine had to be taken in case of pain. The number of tablets taken was used to quantify pain. Swelling of the cheek was measured photographically and trismus was deducible from the maximal mouth-opening. The drugs investigated were: betamethasone 14.5 mg decreasing over 4 days, ibuprofen 1200 mg/day, indomethacin 150 mg/day, naproxen 750 mg/day, niflumic acid 1000 mg/day, oxyphenylbutazone 600 mg/day and tranexamic acid 2000 mg/day. Oxyphenylbutazone and tranexamic acid were not significantly different from placebo in their pain-killing effects. Betamethasone prevents swelling and trismus significantly more than the placebo. Betamethasone is significantly better than the other drugs in the prevention of swelling. Reduction of the swelling by antirheumatics may be 10-15% and a 20% reduction of trismus to be expected. The strongest analgesic niflumic acid. Tranexamic acid may reduce the swelling by 28%. The questionnaire and the blood- and urine-test showed that antirheumatics have to be considered to be acetylsalicylic acid-like drugs. Serious side effects have been reported previously for antirheumatics. When taken for a short time, corticosteroids are very safe drugs with a few mild side effects. Many patients experience a slight euphoria. Betamethasone, in a dosage of 14.5 mg decreasingly divided over 4 days prevents pain by 80%, swelling by 65% and trismus by 40% compared with the placebo group. This safe drug is recommended in elective surgery.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006712198

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Pallavicini M.G.; Deteresa P.S.; Rosette C.; Gray J.W.; Wurm F.M., 1990: Effects of methotrexate on transfected dna stability in mammalian cells. The chromosomal locations, amounts, and level of expression of transfected, amplified c-myc and dihydrofolate reductase sequences were measured in cells cultured in the presence and absence of methotrexate. These studies show that the location and...

Koulouri, Panayota; Dounas, Costas; Eleftheriou, Anastasios, 2013: Hyperbenthic community structure over oligotrophic continental shelves and upper slopes Crete South Aegean Sea, NE Mediterranean. The community structure of hyperbenthos on continental shelves and upper slopes of oligotrophic areas have been little studied. The study, located in the eastern Mediterranean (Heraklion Bay, Crete) gives the first description of this using sample...

Kahn B.A.; Schatzer R.J., 1992: Economic and horticultural evaluation of chemical and mechanical weed control strategies for cowpea. The herbicides paraquat, trifluoralin, and metolachlor were compared for efficacy of weed control in cowpea [Vigna unguiculata (L.) Walp.] with and without cultivation as a supplemental strategy. Herbicides also were compared against a no cultivat...

Nijjar T.S.; Bonacosa I.A.; Israels L.G., 1987: Severe acute thrombocytopenia following infusion of plasma containing p1a 1. An 18-year-old girl with a preoperative platelet count of 216,000/cmm received 3 units of stored plasma at the time of surgery. Within 6 hours her platelet count had fallen to 5,000/mm3 and hemorrhagic manifestations appeared. One of the plasma do...

Irby, L. R., 1977: Food habits of chanlers mountain reedbuck in a rift valley ranch kenya. During 1971-72 contents from the rumens of 22 Chanler's mountin reedbuck (Redunca fulvorufula chanleri Rothschild) collected in the Arthur Cole Ranch near Gilgil, Kenya were examined. Frequency of occurrence of monocots averaged 99.5% of iden...

La Marca, Antonio; Morgante, Giuseppe; Palumbo, Marco; Cianci, Antonio; Petraglia, Felice; De Leo, Vincenzo, 2002: Insulin-lowering treatment reduces aromatase activity in response to follicle-stimulating hormone in women with polycystic ovary syndrome. Objective: To investigate the effects of reduction of insulin resistance and hyperinsulinemia associated with the polycystic ovary syndrome (PCOS) on FSH-stimulated ovarian aromatase activity. Design: Prospective study. Setting: Academic health ce...

Lykov, Am; Emtsev, Vt; Safonov, Af; Al'-Shurai, Aa, 1984: Effect of long-term application of fertilizers and the crop rotation on biological activities of the soil in the cultivation of cereals. Izvestiia Timiriazevskaia sel'skokhoziaistvennaia akademiia: (1) 75-83

Wendt, Dean E.; Johnson, Collin H., 2006: Using latent effects to determine the ecological importance of dissolved organic matter to marine invertebrates. The uptake and utilization of dissolved organic matter (DOM) by marine invertebrates is a field that has received significant attention over the past 100 years. Although it is well established that DOM is taken up by marine invertebrates, the exte...

Depuydt F., 1973: Structure of the lipo polyosides of gram negative bacteria. Archives Internationales De Physiologie Et De Biochimie: 185-186

Van Damme, Kay; Brancelj, Anton; Dumont, Henri J., 2009: Adaptations to the hyporheic in Aloninae Crustacea Cladocera allocation of Alona protzi Hartwig, 1900 and related species to Phreatalona gen nov. Morphological study of Alona protzi Hartwig, 1900, Alona phreatica Dumont, 1983 and Alona smirnovi Petkovski & FloAner, 1972 reveals close affinities with Alona labrosa Vasiljeva & Smirnov, 1969. We separate these four species from the pol...