EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The low molecular weight sulfhydryl protease inhibitor in rat skin is epidermal


, : The low molecular weight sulfhydryl protease inhibitor in rat skin is epidermal. Journal of Investigative Dermatology 71(2): 119-121

The epidermis and dermis of rat skin were separated, and the presence of the high-MW SH-protease inhibitor I1 and the low-MW inhibitor I2 in both was studied. Gel filtrations of the extracts revealed that 97% of the epidermal inhibitor activity was due to I2 and 89% of the dermal activity to I1. The presence of I2 mainly in the epidermis extract was confirmed by immunodiffusion of specific rabbit anti-I2 serum against purified I2, epidermis and dermis extracts and rat serum. Most of the immunoreactive protein was seen in the epidermis extract, traces in the dermis extract and none in the rat serum. I2 was localized in rat skin by indirect immunofluorescence using rabbit anti-I2 serum and fluorescein isothiocyanate conjugate of goat antirabbit immunoglobulins. Intense fluorescence, much brighter than in the controls treated with rabbit nonimmune serum, was seen in the epidermis, being most pronounced in the cytoplasms of cells in the granular layer. The weak fluorescence of the hair follicles, sebaceous glands, connective tissue cells and fibers was unspecific and was also seen in the controls. In view of its epidermal location, the name epidermal SH-protease inhibitor was suggested for I2.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 006712240

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Mourthe, Italo M.C., 2010: Tupinambis merianae common tegu feeding behavior. Herpetological Review: 232-233

Hopkins, T.L., 1969: Zooplankton standing crop in the Arctic basin. Limnologr: 80-85

Mirel R.D.; Ginsberg Fellner F.; Horwitz D.; Rayfield E.J., 1977: C peptide secretory studies in juvenile diabetes evidence for defects in basal and stimulated values. Clinical Research 25(5): 665A

Skamene E., 1988: Genetically determined susceptibility and resistance to diet induced atherosclerosis in inbred strains of mice. To determine whether recombinant inbred strains derived from C57BL/6J and A/J mice would provide a good model in which to study the genetics of diet-induced atherosclerosis, male mice of the parent strains were compared in a number of experiments...

Dayal, J.; Gupta, S. P., 1953: A new trematode, Ganeo gobindia n.sp., (Lecithodendriinac Odhner, 1911) from the intestine of a fresh-water fish, Wallago attu (Bloch.). Ganeo gobindia n.sp. in Wallago attu from the river Gomti, Lucknow, is the first species of this genus to be recorded from a fresh-water fish in India. Only one mature specimen has been found. It differs from G. tigrinum and G. gastricus in the pr...

Carlberg, Hans; Bjornelius, Eva; Jensen, J. S., 2002: Mycoplasma genitalium The search for effective treatment. International Journal of STD & AIDS 13(Supplement 1): 30-31, August

White, J. W.; McMaster, G. S.; Edmeades, G. O., 2004: Genomics and crop response to global change: what have we learned?. Global change poses major challenges for research in fields ranging from crop improvement to water and fertilizer management. Plant genomics is often promoted as a likely source of breakthroughs in understanding plant response to temperature and w...

Eide, Per-Kristian; Due-Tonnessen, Bernt; Helseth, Eirik; Lundar, Tryggve, 2002: Differences in quantitative characteristics of intracranial pressure in hydrocephalic children treated surgically or conservatively. This study reports the results of quantitative analysis of continuous intracranial pressure (ICP) recordings in 33 hydrocephalic children. The aim of the study was to compare the exact numbers of increases in ICP during sleep or the awake state in...

Chaouat, G., 1995: Early immunosuppression and implantation. In this brief review, we recall the antigenic status of the embryo and the possible threats that the maternal immune system poses to fetal survival even at implantation stage. We then quickly recall the existence of Early Pregnancy Factor (EPF), t...

Puchly, S., 1970: An analysis of price influences in output--input models of value of agricultural enterprises. Pol'nohospodarstvo 6 (6) 521-532