+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The low physical working capacity of thyrotoxic patients is not normalized by oral antithyroid treatment

, : The low physical working capacity of thyrotoxic patients is not normalized by oral antithyroid treatment. Clinical Physiology (Oxford) 8(1): 9-16

The low working capacity in thyrotoxic patients has not been quantified and its causes have not been clarified. We studied the working capacity in nine thyrotoxic patients at diagnosis (test 1), after 3 months of oral antithyroid medication (test 2), and in four of them again after 1 year (test 3). The maximum power output was low in thyrotoxic patients (1.65 .+-. 0.15 W/kg-1) and was not significantly higher after 3 months of treatment 1.84 .+-. 0.15), although plasma thyroid hormone concentrations had been normalized for approximately 3 months. After 1 year's treatment the maximum power output was still somewhat low in the four tested patients (2.75 .+-. 0.34). The rate of oxygen uptake under maximum exercise was low (26 ml/min-1/kg-1) and was not significantly increased at test 2 and 3. The net mechanical efficiency was low at test 1 and 2 (18.9 .+-. 2.1% and 20.1 .+-. 1.8%, respectively), but was normal at test 3 (25.2%). At all three tests the blood lactate response upon maximum exercise attained only about 50% of normal concentration. Thus, low work capacity in thyrotoxic patients remained for a long period of time after euthyroid conditions had been attained. The low capacity was due to low aerobic and anaerobic capacities and initially also to a low mechanical efficiency.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 006712244

PMID: 3349759

DOI: 10.1111/j.1475-097x.1988.tb00257.x

Download PDF Full Text: The low physical working capacity of thyrotoxic patients is not normalized by oral antithyroid treatment

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Kraytsberg, Y.; Bodyak, N.; Myerow, S.; Nicholas, A.; Ebralidze, K.; Khrapko, K., 2009: Collection of isolated cells for studying mitochondrial DNA mutations within individual cells. Mitochondrial genome integrity is an important issue in somatic mitochondrial genetics. Development of quantitative methods is indispensable to somatic mitochondrial genetics as quantitative studies are required to characterize heteroplasmy and mu...

Grinevich, V.A.; Gorin, A.G., 1976: Complex treatment of diffuse purulent peritonitis. Klinicheskaia Khirurgiia: 72-73

Dissmann, R.; Linderer, T.; Schröder, R., 1998: Estimation of enzymatic infarct size: direct comparison of the marker enzymes creatine kinase and alpha-hydroxybutyrate dehydrogenase. Background. Estimation of infarct size with serum-time activity curves of creatine kinase (CK) (or CKMB) or alpha-hydroxybutyrate dehydrogenase (HBDH) is widely used in clinical trials. However, an independent variable such as left ventricular fun...

Desiato, R.; Baioni, E.; Cuttica, G.; Sparagna, B.; Berruto, P.; Abete, M.Cesarina.; Bertolini, S.; Maurella, C.; Caramelli, M.; Chiavacci, L.; Ru, G., 2013: Environmental micropollutants in livestock products from Susa Valley, Piedmont. to describe the contamination due to dioxins and dioxin-like PCBs of cattle dairy and meat products in cattle herds from Susa Valley (Piedmont) since the second half of 2004. descriptive study based on a biomonitoring campaign on bovine bulk milk...

Pathiratne, A.; Costa, HH., 1984: Morphological & histological changes in the gonads of the estuarine cichlid fish Etroplus suratensis (Bloch) during gonadal development. Mahasagar, 174: 211-220

Spiliopoulou, A.; Nagy, R.; Bermingham, M.L.; Huffman, J.E.; Hayward, C.; Vitart, V.; Rudan, I.; Campbell, H.; Wright, A.F.; Wilson, J.F.; Pong-Wong, R.; Agakov, F.; Navarro, P.; Haley, C.S., 2016: Genomic prediction of complex human traits: relatedness, trait architecture and predictive meta-models. We explore the prediction of individuals' phenotypes for complex traits using genomic data. We compare several widely used prediction models, including Ridge Regression, LASSO and Elastic Nets estimated from cohort data, and polygenic risk sc...

Wang, W.; He, M.; Zhou, M.; Zhang, X., 2014: Fornix-based versus limbus-based conjunctival flap in trabeculectomy: a quantitative evaluation of the evidence. To evaluate the efficacy and tolerability of limbus-based (LBCF) compared with fornix-based conjunctival flaps (FBCF) for trabeculectomy in the treatment of patients with uncontrolled glaucoma. A comprehensive literature meta-analysis was performe...

Gajewska, E.; Zukowska, H.; Jankowski, A., 1979: Risk of fetal infection and the immunological state of mother and newborn infant. Ginekologia Polska Suppl: 84-87

Gomes, R., 1996: The health-sickness process connected to sexual activity in prostitutes. This articicle is a part of a research focusing on the relationship among child-prostitution, health-sickness-process linked to sexuality and violence; the three categories found in the environment of street girls. This paper, however, only deals...

Antos, F.; Hoch, J., 1989: Sexual disorders after colorectal operations. After extensive colorectal operations there are sexual dysfunctions in the patients in 16-100%. In our cohort of 36 men the post-operation sexual disorders were reported in 21.3%. The authors present an anatomical survey of nerve supply of the org...