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The luffariellins novel antiinflammatory sesterterpenes of chemotaxonomic importance from the marine sponge luffariella variabilis


, : The luffariellins novel antiinflammatory sesterterpenes of chemotaxonomic importance from the marine sponge luffariella variabilis. Journal of Organic Chemistry 52(14): 3081-3083

In some specimens of Luffariella variabilis, manoalide (1) and secomanoalide (2) are replaced, either totally or partially, by luffariellin A (3) and luffariellin B (4), respectively. The structures of luffariellin A (3) and luffariellin B (4) are elucidated by interpretation of spectral data and chemical transformations. Both luffariellin A and luffariellin B are potent antiinflammatory agents.

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Accession: 006712339

DOI: 10.1021/jo00390a021

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