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The luffariellins novel antiinflammatory sesterterpenes of chemotaxonomic importance from the marine sponge luffariella variabilis


Journal of Organic Chemistry 52(14): 3081-3083
The luffariellins novel antiinflammatory sesterterpenes of chemotaxonomic importance from the marine sponge luffariella variabilis
In some specimens of Luffariella variabilis, manoalide (1) and secomanoalide (2) are replaced, either totally or partially, by luffariellin A (3) and luffariellin B (4), respectively. The structures of luffariellin A (3) and luffariellin B (4) are elucidated by interpretation of spectral data and chemical transformations. Both luffariellin A and luffariellin B are potent antiinflammatory agents.

Accession: 006712339

DOI: 10.1021/jo00390a021

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