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The lukes and collins classification on non hodgkins lymphomas 2. a survival study of 301 patients


Acta Pathologica Microbiologica et Immunologica Scandinavica Section A Pathology 90(4): 251-256
The lukes and collins classification on non hodgkins lymphomas 2. a survival study of 301 patients
In a retrospective study of 301 non-Hodgkin's lymphoma patients, the clinical and prognostic value of the classification of Lukes and Collins was studied. A slight majority of the cases were of the follicular center cell [FCC] types. Stage III-IV were found in 46% of the entire group at the time of diagnosis. The lymphomas showing FCC types were frequently localized (63%). Of all cases, .apprx. 65% survived 1 yr and .apprx. 45% survived 5 yr. Females showed a better survival. The nodal lymphoma cases had the poorest survival. Two prognostically different subgroups of non-Hodgkin's lymphomas were discerned. The more favorable group consisted of the small cleaved FCC type (5 yr relative survival, 74%), the small lymphocytic type (62%) and the plasmacytoid lymphocytic type (51%). The small non-cleaved FCC type, the large non-cleaved FCC type and the immunoblastic sarcoma type formed the other group with a less favorable prognosis. Mortality due to these types was 65% in the first 2 yr.


Accession: 006712343

PMID: 7124396



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