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The luteinizing hormone follicle stimulating hormone ratio under basal conditions and after stimulation with gonadotropin releasing hormone in subjects with primary hypo gonadism


, : The luteinizing hormone follicle stimulating hormone ratio under basal conditions and after stimulation with gonadotropin releasing hormone in subjects with primary hypo gonadism. Annales d'Endocrinologie 37(2): 63-73

LH [luteinizing hormone] and FSH [follicle stimulating hormone] behavior was studied under basal conditions and after stimulation with GnRH [gonadotropin-releasing hormone] in groups of subjects exhibiting compromised gonadal activity (subjects of both sexes in old age, affected by Sertoli cells only, Klinefelter's and Turner's syndromes and subjects with congenital anorchia or with rudimentary testes) and compared with that shown by control groups. Special importance was given to the LH/FSH ratio, which was significantly reduced in almost all situations studied. New evidence was obtained to better clarify the mechanism of homeostatic regulation of the gonadotropic incretory system, with special consideration for FSH behavior and useful indications which emphasize the semeiological use of LH/FSH ratio relevant to basal values and to secretory areas.

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