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The lymphocyte response in schizophrenic patients to the phyto mitogens concanavalin a and phyto hem agglutinin


, : The lymphocyte response in schizophrenic patients to the phyto mitogens concanavalin a and phyto hem agglutinin. Byulleten' Eksperimental'noi Biologii i Meditsiny 84(8): 182-185

The capability of the schizophrenic patients' lymphocytes and lymphocytes of healthy persons to respond to concanavalin A and PHA [phytohemagglutinin] was studied. The T[thymus-derived]-cell count was determined by rosette formation; the influence of adhesive cells on the lymphocyte response to mitogens was ascertained. The response to both the mitogens in the patients' lymphocyte cultures was reduced as compared to controls; the T-cell count did not differ. The removal of adherent lymphocytes resulted in the disappearnce of differences between the response of the patients' lymphocytes and normal lymphocytes to the mitogens.

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