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The lymphocyte response in schizophrenic patients to the phyto mitogens concanavalin a and phyto hem agglutinin


, : The lymphocyte response in schizophrenic patients to the phyto mitogens concanavalin a and phyto hem agglutinin. Byulleten' Eksperimental'noi Biologii i Meditsiny 84(8): 182-185

The capability of the schizophrenic patients' lymphocytes and lymphocytes of healthy persons to respond to concanavalin A and PHA [phytohemagglutinin] was studied. The T[thymus-derived]-cell count was determined by rosette formation; the influence of adhesive cells on the lymphocyte response to mitogens was ascertained. The response to both the mitogens in the patients' lymphocyte cultures was reduced as compared to controls; the T-cell count did not differ. The removal of adherent lymphocytes resulted in the disappearnce of differences between the response of the patients' lymphocytes and normal lymphocytes to the mitogens.


Accession: 006712563

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Related references

Kovaleva E.S.; Bonartsev P.D.; Prilipko L.L., 1977: Response of lymphocytes of patients with schizophrenia to phyto mitogens concanavalin a and phyto hem agglutinin. Bulletin of Experimental Biology & Medicine 84(8): (1978)

Stanisz M.; Sabet T.; Hsia W.; E.D.meiri A.; Van Alten P., 1978: Functional considerations of macrophages in the splenic lymphocyte response to the mitogens concanavalin and phyto hem agglutinin p. Federation Proceedings 37(6): 1470

Daunter B.; Khoo S.K.; Mackay E.V., 1979: Lymphocyte response to plant mitogens part 2 the response of lymphocytes from women with carcinoma of the cervix to phyto hem agglutinin p concanavalin a and pokeweed. The lymphocyte response to mitogens was studied in 21 patients with carcinoma of the cervix and in 40 control subjects. The mean log index of the lymphocyte response of the cancer group to phytohemagglutinin (PHA)-P was depressed before and after...

Klinger M., 1980: Response of lymphocytes to nonspecific mitogens phyto hem agglutinin concanavalin a pokeweed mitogen in patients with glomerulo nephritis. Tests on blastic transformation of peripheral blood lymphocytes after stimulation with nonspecific mitogens (PHA [phytohemagglutinin], Con [concanavalin] A, PWM [pokeweed mitogen]) were performed on 55 patients suffering from glomerulonephritis an...

Puppo F.; Corsini G.; Mangini P., 1982: Ranitidine does not modify lymphocyte in vitro reactivity to the mitogens phyto hem agglutinin concanavalin a and pokeweed mitogen. IRCS (International Research Communications System) Medical Science Library Compendium 10(7): 538

Lindahl Kiessling K.; Mattsson A., 1971: Mechanism of phyto hem agglutinin phyto hem agglutinin action part 4 effect of some metabolic inhibitors on binding of phyto hem agglutinin to lymphocytes and the stimulatory potential of phyto hem agglutinin pre treated cells. Experimental Cell Research 65(2): 307-312

Shortman, K.; Ryden, A.; Dunkley, M.; Von-Boehmer, H., 1977: Some requirements for the response of separated thymus derived cell sub populations to the mitogens phyto hem agglutinin and concanavalin a. The proliferative response of various separated populations of mouse spleen and thymus lymphocytes to the mitogen phytohemagglutinin (PHA) was not a direct function of the level of responsive T [thymus-derived] cells, but was governed by other reg...

Berman L.; Andrews M., 1970: The modulation of human lymphocytes in response to phyto hem agglutinin stimulation part 1 observations on the localization of phyto hem agglutinin in leukocyte cultures utilizing fluorescein iso thio cyanate labeled phyto hem agglutinin. RES Journal of the Reticuloendothelial Society 8(1): 74-90

Daunter B.; Khoo S.K.; Mackay E.V., 1979: Lymphocyte response to plant mitogens part 1 the distribution of lymphocyte response to various doses of phyto hem agglutinin m in pregnant women and women with carcinoma of the cervix or ovary. Cell-mediated immune response was measured by the uptake of tritiated thymidine by lymphocytes cultured in serum-free medium in the presence and absence of different doses of phytohemagglutinin (PHA)M. Groups (4) were studied: healthy women (contr...

Gausset P.; Delespesse G.; Duchateau J.; Govaerts A., 1975: Purification characterization and proliferative response to phyto hem agglutinin and concanavalin a of human lymphocyte sub populations. Annales d'Immunologie (Paris) 126C(3): 359-360