EurekaMag.com logo
+ Translate

The lymphocyte transformation test principles and clinical application


, : The lymphocyte transformation test principles and clinical application. Folia Haematologica (Leipzig) 105(4): 449-462

The principle of the lymphocyte transformation test is presented and the present knowledge of the partially selective effect of various nonspecific mitogens on different lymphocyte populations is discussed. Problems of methodology are briefly dealt with and the possibilities of applying the lymphocyte transformation test is given. Clinical examples in patients affected with malignant lymphoma, infectious mononucleosis and polymyositis are reported.

(PDF 0-2 workdays service)

Accession: 006712572

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Yoon, Y.D.; Kim, J.M.; Kim, D.S.; Jeon, Y.S., 1981: Studies on the in vitro lymphocyte transformation test for the development of a subsidiary diagnostic method for bovine tuberculosis. III. In vitro lymphocyte transformation test of peripheral blood lymphocytes from cows with positive, suspicious or negative reactions to the intradermal tuberculin test. The lymphocyte transformation test (see parts I and II--VB 51, abst. 4780) was carried out on 79 tuberculin reactors, of which 40 showed visible lesions and 39 no visible lesions at PM examination. In the 40 cows with visible lesions the average b...

Huber, H.; Huber, C.; Braunsteiner, H., 1966: The clinical significance of lymphocyte culture. In-vitro transformation as a test of lymphocyte function. German Medical Monthly 11(7): 289-292

Yoon, Y.D.; Kim, J.M.; Kim, D.S.; Jeon, Y.S., 1981: In vitro lymphocyte transformation test for the development of the subsidiary diagnostic method of bovine tuberculosis 3. in vitro lymphocyte transformation test of bovine peripheral blood lymphocytes showing positive suspicious and negative reactions by tuberculin intra dermal test. The development of the subsidiary diagnostic method of bovine tuberculosis by in vitro lymphocyte transformation test was reported. Peripheral blood lymphocytes from cows showing positive, suspicious and negative reactions by tuberculin intraderma...

Yoon, Y.D.; Kim, S.H.; Kim, D.S.; Jeon, Y.S., 1980: Studies on the in vitro lymphocyte transformation test for the development of the subsidiary diagnostic method of bovine tuberculosis 1. in vitro lymphocyte transformation test of peripheral blood lymphocytes of mice guinea pigs and cattle sensitized with mycobacterium bovis bcg. The in vitro lymphocyte transformation test was conducted weekly in mice, guinea pigs and cattle sensitized by M. bovis (BCG). The highest blastogenic responses of lymphocytes stimulated with bovine tuberculin purified protein derivative were show...

Li, L.; Zhou, K.X.; Lin, Z.Y., 1987: Application of lymphocyte transformation test to duck. I. Transformation of duck lymphocytes stimulated by PHA: a whole-blood assay incorporated with 3H-TdR. A method of using whole blood for study of phytohaemagglutinin (PHA) stimulation of duck lymphocytes was developed, in which superscript 3H-thymidine (superscript 3H-TdR) was incorporated into lymphocyte DNA for measuring lymphocyte transformation...

Russo, P.; Giauffret, A., 1978: Application of the lymphocyte transformation test to the testing of Chlamydia vaccines. The technique of the lymphoblastic transformation test is described. This test (TTL) was compared with complement fixation and immunofluorescence in ewes vaccinated with a Chlamydia vaccine and tested daily over a period of 6 weeks. A significant...

Petrunov, B.; Konstantinova, D., 1972: Application of the lymphocyte transformation test (LTT) to the diagnosis of pollen allergy. Acta Allergologica 27(3): 229-235

Pappas, A.; Orfanos, C.E.; Bertram, R., 1970: Non-specific lymphocyte transformation in vitro by nickel acetate. A possible source of errors in lymphocyte transformation test (LLT). Journal of Investigative Dermatology 55(3): 198-200

Yoon, Y.D.; Kim, S.H.; Kim, D.S.; Joen, Y.S., 1980: Studies on the in vitro lymphocyte transformation test for the development of the subsidiary diagnostic method of bovine tuberculosis 2. in vitro lymphocyte transformation test of peripheral blood lymphocytes of guinea pigs and cattle sensitized with mycobacterium bovis an 5 and mycobacterium avium d 4. Peripheral blood lymphocytes of guinea-pigs and cattle were sensitized with M. bovis AN5 or M. avium D4 and the cells were stimulated with mammalian and avian PPD [purified protein derivative] tuberculins. The percentage of blast forming cells of...

Yoon, Y.D.; Kim, S.H.; Kim, D.S.; Jeon, Y.S., 1980: Studies on the in vitro lymphocyte transformation test for the development of the subsidiary diagnostic method of bovine tuberculosis. I. In vitro lymphocyte transformation test of peripheral blood lymphocytes of mice, guinea-pig and cattle sensitized with M. bovis (BCG). II. In vitro lymphocyte transformation test of peripheral blood lymphocytes of guinea-pig and cattle sensitized with M. bovis AN5 and M. avium D4. The in vitro lymphocyte transformation test was conducted weekly in mice, guinea pigs and cattle sensitized with M. bovis (BCG). The highest ratios of blastogenic responses of lymphocytes stimulated with bovis PPD tuberculin were found at the 4th...