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The lysozyme content and rheological features of the sputum in patients with chronic bronchitis


Terapevticheskii Arkhiv 58(4): 57-59
The lysozyme content and rheological features of the sputum in patients with chronic bronchitis
The authors presented some data on the lysozyme content and adhesion features of the sputum in 31 patients: 19 patients with chronic obstructive bronchitis and 12 patients with chronic bronchitis against a background of bronchial asthma. Marked reverse correlation between the lysozyme content and sputum adhesion values (r=-0.79) was found. With the subsiding of exacerbation and remission occurrence the lysozyme content increased and a sputum adhesion value reduced. In the exacerbation phase the mean lysozyme content in the sputum was 3.6 .+-. 0.1 mg/mg of protein, and in remission occurrence 6.9 .+-. 0.2 mg/mg of protein. The adhesion value was 0.6 .times. 104 .+-. 0.22 .+-. 104 N/m2 and 0.32 .times. 104 .+-. 0.01 .times. 104 N/m2, respectively. The time course of the lisozyme content in the sputum of patients with chronic bronchitis can be used as a prognostic factor to assess remission occurrence rates and the nature of change of rheological features of the sputum.

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Accession: 006712632



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