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The lysozyme content and rheological features of the sputum in patients with chronic bronchitis


, : The lysozyme content and rheological features of the sputum in patients with chronic bronchitis. Terapevticheskii Arkhiv 58(4): 57-59

The authors presented some data on the lysozyme content and adhesion features of the sputum in 31 patients: 19 patients with chronic obstructive bronchitis and 12 patients with chronic bronchitis against a background of bronchial asthma. Marked reverse correlation between the lysozyme content and sputum adhesion values (r=-0.79) was found. With the subsiding of exacerbation and remission occurrence the lysozyme content increased and a sputum adhesion value reduced. In the exacerbation phase the mean lysozyme content in the sputum was 3.6 .+-. 0.1 mg/mg of protein, and in remission occurrence 6.9 .+-. 0.2 mg/mg of protein. The adhesion value was 0.6 .times. 104 .+-. 0.22 .+-. 104 N/m2 and 0.32 .times. 104 .+-. 0.01 .times. 104 N/m2, respectively. The time course of the lisozyme content in the sputum of patients with chronic bronchitis can be used as a prognostic factor to assess remission occurrence rates and the nature of change of rheological features of the sputum.

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