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Chapter 6,716

The mechanism of botulism

Chao, L.P.

Medical Hypotheses 19(1): 83-87

1986

ISSN/ISBN: 0306-9877
PMID: 3634904
DOI: 10.1016/0306-9877(86)90141-6
Accession: 006715294
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Botulism is induced by botulinum toxin and the mechanism of the disease is unknown. In another study, a fatal autoimmune disease was produced in animals by immunization with a fraction of choline acetyltransferase. When these two syndromes are compared, numerous similarities are observed. It is postulated that botulism toxin acts as an initiator for the autoimmune disease by catalyzing in vivo the formation of the pathogenic fraction of choline acetyltransferase.

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