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The mode of action of cyclic amp in mammalian islets of langerhans effects of insulin secretagogues on islet cell protein kinase activity


, : The mode of action of cyclic amp in mammalian islets of langerhans effects of insulin secretagogues on islet cell protein kinase activity. Biochemical Journal 134(1): 321-327


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Related references

Montague, W.; Howell, S.L., 1973: The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Effects of insulin secretagogues on islet-cell protein kinase activity. 1. Protein kinase activity was measured in islets of Langerhans that had been incubated in the presence of agents known to affect insulin release. 2. Glucagon, theophylline, caffeine and 3-isobutyl-1-methylxanthine, agents that raise cyclic AMP co...

Montague, W.; Howell, S.L., 1972: The mode of action of cyclic amp in mammalian islets of langerhans preparation and properties of islet cell protein phospho kinase. Biochemical Journal 129(3): 551-560

Montague, W.; Howell, S.L., 1972: The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Preparation and properties of islet-cell protein phosphokinase. 1. A protein was demonstrated in mammalian islets of Langerhans that after purification appeared as a single component possessing both cyclic-AMP (adenosine 3':5'-cyclic monophosphate)-binding and cyclic-AMP-dependent protein phosphokina...

Montague, W.; Howell, S.L.; Green, I.C., 1976: Insulin release and the microtubular system of the islets of Langerhans: effects of insulin secretagogues on microtubule subunit pool size. An assay system was devised to estimate the pool size of microtubule subunits in islet cells, and to study the importance of the equilibrium between polymerised microtubules and their subunits in the regulation of insulin release. The assay was ba...

Murphy, L.I.; Jones, P.M., 1995: Effects of insulin secretagogues on phosphoprotein phosphatase 1 and 2A activities in rat islets of Langerhans. Biochemical Society Transactions 23(4): 593s-593s

Hellman, B.; Lernmark, A.; Sehlin, J.; Töljedal, I.B., 1973: The pancreatic beta-cell recognition of insulin secretagogues. Inhibitory effects of a membrane probe on the islet uptake and insulin-releasing action of glibenclamide. Febs Letters 34(2): 347-349

Toeljedal I B., 1973: The pancreatic beta cell recognition of insulin secretagogues inhibitory effects of a membrane probe on the islet uptake and insulin releasing action of glibenclamide. S Letters: 347-349

Easom, R.A.; Landt, M.; Colca, J.R.; Hughes, J.H.; Turk, J.; McDaniel, M., 1990: Effects of insulin secretagogues on protein kinase C-catalyzed phosphorylation of an endogenous substrate in isolated pancreatic islets. The influence of the insulin secretagogues, carbachol and glucose, on protein kinase C activation in isolated pancreatic islets has been examined by determination of the phosphorylation state of an endogenous 80-kDa protein substrate of protein ki...

Tanigawa, K.; Kuzuya, H.; Okamoto, M.; Imura, H., 1983: Effects of insulin secretagogues and inhibitors on phospholipid metabolism in Langerhans' islets of rat pancreas. Glucose stimulation of [32P]-prelabelled pancreatic islets induced an increased incorporation of radioactivity into phosphatidylinositol. Glucagon and agents that increases cAMP in the islet did not affect phosphatidylinositol turnover, in spite o...

Alden W.W.; Taylor K.W.; Festenstein H., 1986: The effects of viral infection and islet cell antibodies on cell mediated lymphotoxicity and insulin biosynthesis in human and rodent islets of langerhans. Clinical Science (London) 70(SUPPL 13): 59P